Sirolimus

mechanistic target of rapamycin kinase ; Homo sapiens







2470 Article(s)
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Title
Pub. Year
#Total Relationships
2451 10359590 Transformation by v-Src: Ras-MAPK and PI3K-mTOR mediate parallel pathways. 1999 Jun 1
2452 10446965 Regulation of cell growth and cyclin D1 expression by the constitutively active FRAP-p70s6K pathway in human pancreatic cancer cells. 1999 Aug 1 1
2453 10490847 Characterization of S6K2, a novel kinase homologous to S6K1. 1999 Sep 9 1
2454 10499523 Endothelin-mediated vascular growth requires p42/p44 mitogen-activated protein kinase and p70 S6 kinase cascades via transactivation of epidermal growth factor receptor. 1999 Oct 1
2455 10551813 Hydrogen peroxide activates p70(S6k) signaling pathway. 1999 Nov 12 1
2456 10567431 Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro. 1999 Nov 26 2
2457 10574945 Mammalian TOR controls one of two kinase pathways acting upon nPKCdelta and nPKCepsilon. 1999 Dec 3 2
2458 9621041 Rapamycin and wortmannin enhance replication of a defective encephalomyocarditis virus. 1998 Jul 1
2459 9636226 Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway. 1998 Jun 23 1
2460 9722592 mu-Opioid receptor activates signaling pathways implicated in cell survival and translational control. 1998 Sep 4 2
2461 9792703 Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway. 1998 Nov 6 1
2462 9852118 Attenuation of mammalian target of rapamycin activity by increased cAMP in 3T3-L1 adipocytes. 1998 Dec 18 2
2463 9249059 Distinct repression of translation by wortmannin and rapamycin. 1997 Jul 1 1
2464 9334222 Regulation of eIF-4E BP1 phosphorylation by mTOR. 1997 Oct 17 6
2465 9434772 Expression, enzyme activity, and subcellular localization of mammalian target of rapamycin in insulin-responsive cells. 1997 Dec 29 3
2466 8595879 Mammalian RAFT1 kinase domain provides rapamycin-sensitive TOR function in yeast. 1996 Feb 1 1
2467 8662507 Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP. 1996 Jul 12 2
2468 7673106 The rapamycin and FKBP12 target (RAFT) displays phosphatidylinositol 4-kinase activity. 1995 Sep 8 2
2469 9383417 Design and synthesis of a rapamycin-based high affinity binding FKBP12 ligand. 1995 Mar 1
2470 7518356 RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs. 1994 Jul 15 1