Title : Transformation by v-Src: Ras-MAPK and PI3K-mTOR mediate parallel pathways.

Pub. Date : 1999 Jun

PMID : 10359590






1 Functional Relationships(s)
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1 Similarly, inhibition of the PI3K-mTOR pathway by addition of the PI3K inhibitor 2-[4-morpholinyl]-8-phenyl-4H-1-benzopyran-4-one (LY294002) or the mTOR inhibitor rapamycin, although reducing several parameters of transformation, also failed to block transformation. Sirolimus mechanistic target of rapamycin kinase Homo sapiens