| 1 |
34403298 | Torin 1 alleviates impairment of TFEB-mediated lysosomal biogenesis and autophagy in TGFBI (p.G623_H626del)-linked Thiel-Behnke corneal dystrophy. | 2022 Apr |
1 |
| 2 |
34654720 | Enhanced Vulnerability of LKB1-Deficient NSCLC to Disruption of ATP Pools and Redox Homeostasis by 8-Cl-Ado. | 2022 Feb |
1 |
| 3 |
34985718 | Oxadiazol-based mTOR inhibitors with potent antiproliferative activities: synthetic and computational modeling. | 2022 Jan 5 |
2 |
| 4 |
35069879 | CRNDE silencing promotes apoptosis and enhances cisplatin sensitivity of colorectal carcinoma cells by inhibiting the Akt/mTORC1-mediated Warburg effect. | 2022 Feb |
1 |
| 5 |
35165269 | The synergistic antitumor effect of IL-6 neutralization with NVP-BEZ235 in hepatocellular carcinoma. | 2022 Feb 14 |
1 |
| 6 |
35222389 | CD39/CD73 Dysregulation of Adenosine Metabolism Increases Decidual Natural Killer Cell Cytotoxicity: Implications in Unexplained Recurrent Spontaneous Abortion. | 2022 |
1 |
| 7 |
35319356 | The ATP-dependent pathways and human diseases. | 2022 Mar 22 |
1 |
| 8 |
32627660 | Regulation and repurposing of nutrient sensing and autophagy in innate immunity. | 2021 Jul |
1 |
| 9 |
33390782 | Comparing mTOR inhibitor Rapamycin with Torin-2 within the RIST molecular-targeted regimen in neuroblastoma cells. | 2021 |
1 |
| 10 |
33445220 | Donor genetic variants as risk factors for thrombosis after liver transplantation: A genome-wide association study. | 2021 Sep |
1 |
| 11 |
33686292 | A compendium of kinetic modulatory profiles identifies ferroptosis regulators. | 2021 Jun |
2 |
| 12 |
33801030 | Marine-Derived Natural Products as ATP-Competitive mTOR Kinase Inhibitors for Cancer Therapeutics. | 2021 Mar 21 |
3 |
| 13 |
33860865 | Activated p53 in the anti-apoptotic milieu of tuberous sclerosis gene mutation induced diseases leads to cell death if thioredoxin reductase is inhibited. | 2021 Jun |
1 |
| 14 |
34047935 | Mechanism of insulin resistance in obesity: a role of ATP. | 2021 Jun |
1 |
| 15 |
34114360 | Chemical and Structural Strategies to Selectively Target mTOR Kinase. | 2021 Sep 16 |
2 |
| 16 |
34445471 | Evaluation of the Binding Kinetics of RHEB with mTORC1 by In-Cell and In Vitro Assays. | 2021 Aug 16 |
4 |
| 17 |
34523696 | Targeting the mTOR pathway using novel ATP‑competitive inhibitors, Torin1, Torin2 and XL388, in the treatment of glioblastoma. | 2021 Oct |
1 |
| 18 |
34674743 | AZD2014, a dual mTOR inhibitor, attenuates cardiac hypertrophy in vitro and in vivo. | 2021 Oct 21 |
1 |
| 19 |
34853384 | Emergence of mTOR mutation as an acquired resistance mechanism to AKT inhibition, and subsequent response to mTORC1/2 inhibition. | 2021 Dec 1 |
2 |
| 20 |
34913837 | Binding site hotspot map of PI3Kα and mTOR in the presence of selective and dual ATP-competitive inhibitors. | 2021 Dec 16 |
2 |
| 21 |
34987473 | Mitochondria in Sex Hormone-Induced Disorder of Energy Metabolism in Males and Females. | 2021 |
1 |
| 22 |
31793691 | mTOR-mediated metabolic reprogramming shapes distinct microglia functions in response to lipopolysaccharide and ATP. | 2020 May |
5 |
| 23 |
31894316 | Anti‑proliferative effect of cardamonin on mTOR inhibitor‑resistant cancer cells. | 2020 Mar |
3 |
| 24 |
31955578 | Discovery of a Brain-Penetrant ATP-Competitive Inhibitor of the Mechanistic Target of Rapamycin (mTOR) for CNS Disorders. | 2020 Feb 13 |
3 |
| 25 |
32054096 | c-Jun, Foxo3a, and c-Myc Transcription Factors are Key Regulators of ATP-Mediated Angiogenic Responses in Pulmonary Artery Vasa Vasorum Endothelial Cells. | 2020 Feb 11 |
2 |
| 26 |
32058927 | Transcriptome profiling of tolerogenic dendritic cells conditioned with dual mTOR kinase inhibitor, AZD8055. | 2020 Apr |
2 |
| 27 |
32132037 | Antihelminthic Niclosamide Induces Autophagy and Delayed Apoptosis in Human Non-small Lung Cancer Cells In Vitro and In Vivo. | 2020 Mar |
1 |
| 28 |
32323755 | AMPK activation protects astrocytes from hypoxia‑induced cell death. | 2020 May |
2 |
| 29 |
32347294 | Small molecule H89 renders the phosphorylation of S6K1 and AKT resistant to mTOR inhibitors. | 2020 May 29 |
1 |
| 30 |
32431177 | Advances in mammalian target of rapamycin kinase inhibitors: application to devices used in the treatment of coronary artery disease. | 2020 Jun |
2 |
| 31 |
32440103 | Virtual Screening and Optimization of Novel mTOR Inhibitors for Radiosensitization of Hepatocellular Carcinoma. | 2020 |
1 |
| 32 |
32514232 | Virtual docking screening and QSAR studies to explore AKT and mTOR inhibitors acting on PI3K in cancers. | 2020 |
2 |
| 33 |
32586228 | Manipulating Cellular Energetics to Slow Aging of Tissues and Organs. | 2020 Jun |
1 |
| 34 |
32913468 | Torin2 inhibits the EGFR-TKI resistant Non-Small Lung Cancer cell proliferation through negative feedback regulation of Akt/mTOR signaling. | 2020 |
1 |
| 35 |
32966896 | Research progress of mTOR inhibitors. | 2020 Dec 15 |
1 |
| 36 |
33116421 | ISL Induces Apoptosis and Autophagy in Hepatocellular Carcinoma via Downregulation of PI3K/AKT/mTOR Pathway in vivo and in vitro. | 2020 |
4 |
| 37 |
33154352 | GDC-0349 inhibits non-small cell lung cancer cell growth. | 2020 Nov 5 |
1 |
| 38 |
33159013 | The therapeutic value of XL388 in human glioma cells. | 2020 Nov 6 |
1 |
| 39 |
33255925 | A Novel Pipeline for Drug Repurposing for Bladder Cancer Based on Patients' Omics Signatures. | 2020 Nov 26 |
1 |
| 40 |
30602778 | The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis. | 2019 Jan 2 |
1 |
| 41 |
30633777 | Impaired autophagic and mitochondrial functions are partially restored by ERT in Gaucher and Fabry diseases. | 2019 |
1 |
| 42 |
30682771 | mTOR Inhibitors in Advanced Biliary Tract Cancers. | 2019 Jan 24 |
1 |
| 43 |
30782662 | Targeting mTOR with MLN0128 Overcomes Rapamycin and Chemoresistant Primary Effusion Lymphoma. | 2019 Feb 19 |
1 |
| 44 |
30787971 | NVP-BEZ235-induced autophagy as a potential therapeutic approach for multiple myeloma. | 2019 |
1 |
| 45 |
31010692 | Diverse signaling mechanisms of mTOR complexes: mTORC1 and mTORC2 in forming a formidable relationship. | 2019 May |
2 |
| 46 |
31082764 | Design, synthesis and pharmacological evaluation of a novel mTOR-targeted anti-EV71 agent. | 2019 Aug 1 |
1 |
| 47 |
31164892 | ATP Triggers Human Th9 Cell Differentiation via Nitric Oxide-Mediated mTOR-HIF1α Pathway. | 2019 |
2 |
| 48 |
31244838 | Mammalian Target of Rapamycin (mTOR) and the Proteasome Attenuates IL-1β Expression in Primary Mouse Cardiac Fibroblasts. | 2019 |
1 |
| 49 |
31246453 | Progress toward the Total Synthesis of Lymphostins: Preparation of a Functionalized Tetrahydropyrrolo[4,3,2-de]quinoline and Unusual Oxidative Dimerization. | 2019 Jul 19 |
1 |
| 50 |
31307011 | The role of an anti-diabetic drug metformin in the treatment of endocrine tumors. | 2019 Aug |
1 |