|  201  | 
				   20028854   |   AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity.  |   2010 Jan 1  | 
				   2   | 
			
		
			
				|  202  | 
				   20089401   |   Pyrazolopyrimidines as highly potent and selective, ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR): optimization of the 1-substituent.  |   2010 Feb 15  | 
				   2   | 
			
		
			
				|  203  | 
				   20166697   |   Bis(morpholino-1,3,5-triazine) derivatives: potent adenosine 5'-triphosphate competitive phosphatidylinositol-3-kinase/mammalian target of rapamycin inhibitors: discovery of compound 26 (PKI-587), a highly efficacious dual inhibitor.  |   2010 Mar 25  | 
				   1   | 
			
		
			
				|  204  | 
				   20187447   |   [Adenosine-triphosphate promoting repair of spinal cord injury by activating mammalian target of rapamycin/signal transducers and activators of transcription 3 signal pathway in rats].  |   2010 Feb  | 
				   3   | 
			
		
			
				|  205  | 
				   20188551   |   4-Substituted-7-azaindoles bearing a ureidobenzofuranone moiety as potent and selective, ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR).  |   2010 Apr 1  | 
				   2   | 
			
		
			
				|  206  | 
				   20188552   |   Discovery and optimization of 2-(4-substituted-pyrrolo[2,3-b]pyridin-3-yl)methylene-4-hydroxybenzofuran-3(2H)-ones as potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR).  |   2010 Apr 1  | 
				   4   | 
			
		
			
				|  207  | 
				   20223663   |   2-Arylureidophenyl-4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)triazines as highly potent and selective ATP competitive mTOR inhibitors: optimization of human microsomal stability.  |   2010 Apr 15  | 
				   1   | 
			
		
			
				|  208  | 
				   20549474   |   New inhibitors of the PI3K-Akt-mTOR pathway: insights into mTOR signaling from a new generation of Tor Kinase Domain Inhibitors (TORKinibs).  |   2010  | 
				   2   | 
			
		
			
				|  209  | 
				   20569080   |   New inhibitors of the mammalian target of rapamycin signaling pathway for cancer.  |   2010 Aug  | 
				   2   | 
			
		
			
				|  210  | 
				   20597028   |   Recent advances in the development of selective, ATP-competitive inhibitors of mTOR.  |   2010 Jul  | 
				   2   | 
			
		
			
				|  211  | 
				   20678995   |   ATP-mediated protein kinase B Akt/mammalian target of rapamycin mTOR/p70 ribosomal S6 protein p70S6 kinase signaling pathway activation promotes improvement of locomotor function after spinal cord injury in rats.  |   2010 Sep 1  | 
				   1   | 
			
		
			
				|  212  | 
				   20804212   |   Steady-state kinetic and inhibition studies of the mammalian target of rapamycin (mTOR) kinase domain and mTOR complexes.  |   2010 Oct 5  | 
				   3   | 
			
		
			
				|  213  | 
				   20812900   |   Updates of mTOR inhibitors.  |   2010 Sep  | 
				   2   | 
			
		
			
				|  214  | 
				   20884625   |   Dual inhibition of PI3K and mTORC1/2 signaling by NVP-BEZ235 as a new therapeutic strategy for acute myeloid leukemia.  |   2010 Nov 15  | 
				   1   | 
			
		
			
				|  215  | 
				   21062993   |   Akt and autophagy cooperate to promote survival of drug-resistant glioma.  |   2010 Nov 9  | 
				   1   | 
			
		
			
				|  216  | 
				   19150980   |   An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1.  |   2009 Mar 20  | 
				   2   | 
			
		
			
				|  217  | 
				   19209957   |   Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2.  |   2009 Feb 10  | 
				   1   | 
			
		
			
				|  218  | 
				   19416948   |   Antagonism of the mammalian target of rapamycin selectively mediates metabolic effects of epidermal growth factor receptor inhibition and protects human malignant glioma cells from hypoxia-induced cell death.  |   2009 Jun  | 
				   1   | 
			
		
			
				|  219  | 
				   19442097   |   Diabetes, oxidative stress, nitric oxide and mitochondria function.  |   2009 May  | 
				   1   | 
			
		
			
				|  220  | 
				   19507259   |   Enhanced IFNgamma production in adenosine-treated CHO cells: a mechanistic study.  |   2009 May-Jun  | 
				   1   | 
			
		
			
				|  221  | 
				   19584280   |   Biochemical, cellular, and in vivo activity of novel ATP-competitive and selective inhibitors of the mammalian target of rapamycin.  |   2009 Aug 1  | 
				   2   | 
			
		
			
				|  222  | 
				   19645448   |   ATP-competitive inhibitors of the mammalian target of rapamycin: design and synthesis of highly potent and selective pyrazolopyrimidines.  |   2009 Aug 27  | 
				   2   | 
			
		
			
				|  223  | 
				   19894727   |   Discovery of 4-morpholino-6-aryl-1H-pyrazolo[3,4-d]pyrimidines as highly potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR): optimization of the 6-aryl substituent.  |   2009 Dec 24  | 
				   2   | 
			
		
			
				|  224  | 
				   19901542   |   Targeting mTOR globally in cancer: thinking beyond rapamycin.  |   2009 Dec  | 
				   2   | 
			
		
			
				|  225  | 
				   20622997   |   mTOR Mediated Anti-Cancer Drug Discovery.  |   2009 Summer  | 
				   1   | 
			
		
			
				|  226  | 
				   18247380   |   Modulation of the activities of AMP-activated protein kinase, protein kinase B, and mammalian target of rapamycin by limiting energy availability with 2-deoxyglucose.  |   2008 Aug  | 
				   2   | 
			
		
			
				|  227  | 
				   18401543   |   The metabolism of proline, a stress substrate, modulates carcinogenic pathways.  |   2008 Nov  | 
				   1   | 
			
		
			
				|  228  | 
				   18606717   |   Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity.  |   2008 Jul  | 
				   1   | 
			
		
			
				|  229  | 
				   18701474   |   S6K1 plays a key role in glial transformation.  |   2008 Aug 15  | 
				   2   | 
			
		
			
				|  230  | 
				   19568796   |   Rapamycin and mTOR kinase inhibitors.  |   2008 Nov  | 
				   1   | 
			
		
			
				|  231  | 
				   17244528   |   Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2.  |   2007 Jan 26  | 
				   1   | 
			
		
			
				|  232  | 
				   16847060   |   The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity.  |   2006 Sep 15  | 
				   2   | 
			
		
			
				|  233  | 
				   15522879   |   Extracellular ATP-induced proliferation of adventitial fibroblasts requires phosphoinositide 3-kinase, Akt, mammalian target of rapamycin, and p70 S6 kinase signaling pathways.  |   2005 Jan 21  | 
				   5   | 
			
		
			
				|  234  | 
				   15797443   |   Central roles of Mg2+ and MgATP2- in the regulation of protein synthesis and cell proliferation: significance for neoplastic transformation.  |   2005  | 
				   1   | 
			
		
			
				|  235  | 
				   16027121   |   Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity.  |   2005 Sep 16  | 
				   1   | 
			
		
			
				|  236  | 
				   16193082   |   Synergistic effect of targeting mTOR by rapamycin and depleting ATP by inhibition of glycolysis in lymphoma and leukemia cells.  |   2005 Dec  | 
				   3   | 
			
		
			
				|  237  | 
				   14560960   |   Role of mTOR signalling in the control of translation initiation and elongation by nutrients.  |   2004  | 
				   1   | 
			
		
			
				|  238  | 
				   14560964   |   mTOR: a mediator of intracellular homeostasis.  |   2004  | 
				   2   | 
			
		
			
				|  239  | 
				   14684182   |   mTOR integrates amino acid- and energy-sensing pathways.  |   2004 Jan 9  | 
				   2   | 
			
		
			
				|  240  | 
				   14761947   |   Extracellular ATP-mediated signaling for survival in hyperoxia-induced oxidative stress.  |   2004 Apr 16  | 
				   1   | 
			
		
			
				|  241  | 
				   15024032   |   In vitro FRAP reveals the ATP-dependent nuclear mobilization of the exon junction complex protein SRm160.  |   2004 Mar 15  | 
				   1   | 
			
		
			
				|  242  | 
				   15561916   |   Signaling elements involved in the metabolic regulation of mTOR by nutrients, incretins, and growth factors in islets.  |   2004 Dec  | 
				   2   | 
			
		
			
				|  243  | 
				   11930000   |   FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction.  |   2002 Apr 2  | 
				   1   | 
			
		
			
				|  244  | 
				   12387821   |   Translational initiation regulators are hypophosphorylated in rat liver during ethionine-mediated ATP depletion.  |   2002 Oct 25  | 
				   2   | 
			
		
			
				|  245  | 
				   11691993   |   Mammalian TOR: a homeostatic ATP sensor.  |   2001 Nov 2  | 
				   3   |