| 1 |
33888713 | Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer. | 2021 Apr 22 |
1 |
| 2 |
34433044 | Loss of tyrosine catabolic enzyme HPD promotes glutamine anaplerosis through mTOR signaling in liver cancer. | 2021 Aug 24 |
1 |
| 3 |
34634301 | Tyrosine phosphorylation of DEPTOR functions as a molecular switch to activate mTOR signaling. | 2021 Nov |
3 |
| 4 |
34731599 | Loss of tyrosine catabolic enzyme HPD promotes glutamine anaplerosis through mTOR signaling in liver cancer. | 2021 Nov 2 |
1 |
| 5 |
34928935 | tRNA biogenesis and specific aminoacyl-tRNA synthetases regulate senescence stability under the control of mTOR. | 2021 Dec |
1 |
| 6 |
31751860 | Somatic copy number alterations are associated with EGFR amplification and shortened survival in patients with primary glioblastoma. | 2020 Jan |
1 |
| 7 |
32386023 | High glucose up-regulates MMP-1 expression in endothelial cells via mTORC2-PKM2 pathway. | 2020 Mar 28 |
1 |
| 8 |
29453318 | Integration of Distinct ShcA Signaling Complexes Promotes Breast Tumor Growth and Tyrosine Kinase Inhibitor Resistance. | 2018 May |
1 |
| 9 |
30466782 | Prolonged MEK inhibition leads to acquired resistance and increased invasiveness in KRAS mutant gastric cancer. | 2018 Dec 9 |
1 |
| 10 |
26584640 | mTORC2 promotes type I insulin-like growth factor receptor and insulin receptor activation through the tyrosine kinase activity of mTOR. | 2016 Jan |
1 |
| 11 |
26584641 | mTORC2 is a tyrosine kinase. | 2016 Jan |
1 |
| 12 |
27385486 | Mutant p53 and mTOR/PKM2 regulation in cancer cells. | 2016 Sep |
1 |
| 13 |
24366666 | cdc-like/dual-specificity tyrosine phosphorylation-regulated kinases inhibitor leucettine L41 induces mTOR-dependent autophagy: implication for Alzheimer's disease. | 2014 Mar |
1 |
| 14 |
24652289 | Insulin and metabolic stress stimulate multisite serine/threonine phosphorylation of insulin receptor substrate 1 and inhibit tyrosine phosphorylation. | 2014 May 2 |
2 |
| 15 |
22281494 | Improved insulin sensitivity by rapamycin is associated with reduction of mTOR and S6K1 activities in L6 myotubes. | 2012 Feb 10 |
1 |
| 16 |
20594757 | mTOR partly mediates insulin resistance by phosphorylation of insulin receptor substrate-1 on serine(307) residues after burn. | 2011 Feb |
1 |
| 17 |
21807000 | Orthovanadate-induced cell death in RET/PTC1-harboring cancer cells involves the activation of caspases and altered signaling through PI3K/Akt/mTOR. | 2011 Sep 12 |
1 |
| 18 |
20203102 | Chronic inhibition of the mTORC1/S6K1 pathway increases insulin-induced PI3K activity but inhibits Akt2 and glucose transport stimulation in 3T3-L1 adipocytes. | 2010 Apr |
1 |
| 19 |
20298531 | Methylnaltrexone potentiates the anti-angiogenic effects of mTOR inhibitors. | 2010 Feb 19 |
3 |
| 20 |
21129605 | The therapy of kidney cancer with biomolecular drugs. | 2010 Nov |
1 |
| 21 |
19435852 | The action of leptin in the ventral tegmental area to decrease food intake is dependent on Jak-2 signaling. | 2009 Jul |
1 |
| 22 |
18663086 | Suppression of c-Cbl tyrosine phosphorylation inhibits neointimal formation in balloon-injured rat arteries. | 2008 Aug 12 |
2 |
| 23 |
18687633 | Laser capture microdissection and protein microarray analysis of human non-small cell lung cancer: differential epidermal growth factor receptor (EGPR) phosphorylation events associated with mutated EGFR compared with wild type. | 2008 Oct |
6 |
| 24 |
17585318 | Phosphorylation profiles of protein kinases in alveolar and embryonal rhabdomyosarcoma. | 2007 Sep |
1 |
| 25 |
16159962 | Regulation of focal adhesion dynamics and disassembly by phosphorylation of FAK at tyrosine 397. | 2005 Oct 1 |
1 |
| 26 |
14560963 | Kinase activities associated with mTOR. | 2004 |
1 |
| 27 |
12730242 | Hyperosmotic stress inhibits insulin receptor substrate-1 function by distinct mechanisms in 3T3-L1 adipocytes. | 2003 Jul 18 |
1 |
| 28 |
11162588 | Frap-dependent serine phosphorylation of IRS-1 inhibits IRS-1 tyrosine phosphorylation. | 2001 Jan 26 |
4 |
| 29 |
11287630 | A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1. | 2001 Apr 10 |
2 |