Title : Orthovanadate-induced cell death in RET/PTC1-harboring cancer cells involves the activation of caspases and altered signaling through PI3K/Akt/mTOR.

Pub. Date : 2011 Sep 12

PMID : 21807000






1 Functional Relationships(s)
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Compound Name
Protein Name
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1 The resulting protein, mainly through tyrosine 451, is responsible for the activation of pathways controlling cell survival, including the PI3K/Akt/mTOR cascade. Tyrosine mechanistic target of rapamycin kinase Homo sapiens