epigallocatechin gallate

mechanistic target of rapamycin kinase ; Homo sapiens







31 Article(s)
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1 34314931 Stability and antioxidant capacity of epigallocatechin gallate in Dulbecco's modified eagle medium. 2022 Jan 1 2
2 35487599 EGCG and ECG induce apoptosis and decrease autophagy via the AMPK/mTOR and PI3K/AKT/mTOR pathway in human melanoma cells. 2022 Apr 5
3 34836374 Role of Epigallocatechin Gallate in Glucose, Lipid, and Protein Metabolism and L-Theanine in the Metabolism-Regulatory Effects of Epigallocatechin Gallate. 2021 Nov 17 1
4 31554961 ERK1/2-HNF4α axis is involved in epigallocatechin-3-gallate inhibition of HBV replication. 2020 Feb 1
5 31918176 From tea to treatment; epigallocatechin gallate and its potential involvement in minimizing the metabolic changes in cancer. 2020 Feb 1
6 32236585 PTEN/AKT/mTOR signaling mediates anticancer effects of epigallocatechin‑3‑gallate in ovarian cancer. 2020 Jun 1
7 32257052 RNA-seq data analysis of stimulated hepatocellular carcinoma cells treated with epigallocatechin gallate and fisetin reveals target genes and action mechanisms. 2020 2
8 32272164 A new epigallocatechin gallate derivative isolated from Anhua dark tea sensitizes the chemosensitivity of gefitinib via the suppression of PI3K/mTOR and epithelial-mesenchymal transition. 2020 Jun 1
9 32309347 EGCG protects vascular endothelial cells from oxidative stress-induced damage by targeting the autophagy-dependent PI3K-AKT-mTOR pathway. 2020 Mar 6
10 30456590 Epigallocatechin gallate suppresses premature senescence of preadipocytes by inhibition of PI3K/Akt/mTOR pathway and induces senescent cell death by regulation of Bax/Bcl-2 pathway. 2019 Apr 3
11 29636854 Epigallocatechin-3-Gallate (EGCG) Promotes Autophagy-Dependent Survival via Influencing the Balance of mTOR-AMPK Pathways upon Endoplasmic Reticulum Stress. 2018 5
12 29163766 Epigallocatechin-3-gallate (EGCG) up-regulates miR-15b expression thus attenuating store operated calcium entry (SOCE) into murine CD4+ T cells and human leukaemic T cell lymphoblasts. 2017 Oct 27 1
13 27176210 (‑)‑Epigallocatechin‑3‑gallate induces apoptosis in human pancreatic cancer cells via PTEN. 2016 Jul 5
14 27246989 Epigallocatechin gallate exerts protective effects against myocardial ischemia/reperfusion injury through the PI3K/Akt pathway-mediated inhibition of apoptosis and the restoration of the autophagic flux. 2016 Jul 2
15 26298529 Screening of multi-targeted natural compounds for receptor tyrosine kinases inhibitors and biological evaluation on cancer cell lines, in silico and in vitro. 2015 Sep 1
16 25123131 A combination of eicosapentaenoic acid-free fatty acid, epigallocatechin-3-gallate and proanthocyanidins has a strong effect on mTOR signaling in colorectal cancer cells. 2014 Oct 3
17 25169472 The mTOR signalling pathway in cancer and the potential mTOR inhibitory activities of natural phytochemicals. 2014 1
18 25988128 Enhancement of Cisplatin sensitivity in human cervical cancer: epigallocatechin-3-gallate. 2014 1
19 22350026 Epigallocatechin-3-gallate potentiates curcumin's ability to suppress uterine leiomyosarcoma cell growth and induce apoptosis. 2013 Jun 1
20 23711146 PI3K/AKT/mTOR signaling is involved in (-)-epigallocatechin-3-gallate-induced apoptosis of human pancreatic carcinoma cells. 2013 7
21 23916613 Epigallocatechin-gallate (EGCG) regulates autophagy in human retinal pigment epithelial cells: a potential role for reducing UVB light-induced retinal damage. 2013 Sep 6 2
22 22459208 Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells. 2012 May 1 1
23 22769244 Different fatty acid metabolism effects of (-)-epigallocatechin-3-gallate and C75 in adenocarcinoma lung cancer. 2012 Jul 6 1
24 22843790 Epigallocatechin-3-gallate diminishes cytokine-stimulated Cyr61 expression in human osteoblastic cells: a therapeutic potential for arthritis. 2012 Nov 1
25 21300025 Epigallocatechin gallate (EGCG), a major component of green tea, is a dual phosphoinositide-3-kinase/mTOR inhibitor. 2011 Mar 11 7
26 20140007 Epigallocatechin-3-gallate (EGCG) attenuates inflammation in MRL/lpr mouse mesangial cells. 2010 Mar 2
27 20812900 Updates of mTOR inhibitors. 2010 Sep 2
28 21318151 Green tea epigallocatechin gallate exhibits anticancer effect in human pancreatic carcinoma cells via the inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor. 2010 1
29 16862172 Green tea polyphenol EGCG suppresses cigarette smoke condensate-induced NF-kappaB activation in normal human bronchial epithelial cells. 2007 Feb 1 2
30 16731755 Green tea extract and (-)-epigallocatechin-3-gallate inhibit hypoxia- and serum-induced HIF-1alpha protein accumulation and VEGF expression in human cervical carcinoma and hepatoma cells. 2006 May 1
31 16841034 Green tea extract and (-)-epigallocatechin-3-gallate inhibit mast cell-stimulated type I collagen expression in keloid fibroblasts via blocking PI-3K/AkT signaling pathways. 2006 Dec 1