Pub. Date : 2022 Apr
PMID : 35487599
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | EGCG and ECG induce apoptosis and decrease autophagy via the AMPK/mTOR and PI3K/AKT/mTOR pathway in human melanoma cells. | epigallocatechin gallate | mechanistic target of rapamycin kinase | Homo sapiens |
| 2 | EGCG and ECG induce apoptosis and decrease autophagy via the AMPK/mTOR and PI3K/AKT/mTOR pathway in human melanoma cells. | epigallocatechin gallate | mechanistic target of rapamycin kinase | Homo sapiens |
| 3 | Mechanistically, EGCG and ECG treatments decreased phosphorylated-AMPK (p-AMPK) and increased the ratios of p-PI3K, p-AKT and p-mTOR in melanoma cells. | epigallocatechin gallate | mechanistic target of rapamycin kinase | Homo sapiens |
| 4 | Conclusively, EGCG and ECG induced apoptosis via mitochondrial signaling pathway, downregulated autophagy through modulating the AMPK/mTOR and PI3K/AKT/mTOR signaling pathway. | epigallocatechin gallate | mechanistic target of rapamycin kinase | Homo sapiens |
| 5 | Conclusively, EGCG and ECG induced apoptosis via mitochondrial signaling pathway, downregulated autophagy through modulating the AMPK/mTOR and PI3K/AKT/mTOR signaling pathway. | epigallocatechin gallate | mechanistic target of rapamycin kinase | Homo sapiens |