Cyclosporine

solute carrier organic anion transporter family member 1B1 ; Homo sapiens







34 Article(s)
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1 35241487 Experimental and Modeling Evidence Supporting the Trans-Inhibition Mechanism for Preincubation Time-Dependent, Long-Lasting Inhibition of Organic Anion Transporting Polypeptide 1B1 by Cyclosporine A. 2022 May 10
2 31901416 Recent advances in preclinical in vitro approaches towards quantitative prediction of hepatic clearance and drug-drug interactions involving organic anion transporting polypeptide (OATP) 1B transporters. 2020 Feb 1
3 30982223 Organic Anion Transporter Polypeptide 1B1 Polymorphism Modulates the Extent of Drug-Drug Interaction and Associated Biomarker Levels in Healthy Volunteers. 2019 Jul 5
4 31703927 Short-lasting inhibition of hepatic uptake transporter OATP1B1 by tyrosine kinase inhibitor pazopanib. 2019 Dec 1
5 29255993 Prevalence and nature of statin drug-drug interactions in a university hospital by electronic health record mining. 2018 Apr 1
6 29712725 Quantitative Analysis of Complex Drug-Drug Interactions between Cerivastatin and Metabolism/Transport Inhibitors Using Physiologically Based Pharmacokinetic Modeling. 2018 Jul 3
7 26961540 Identification of Transporters Involved in Beraprost Sodium Transport In Vitro. 2017 Feb 1
8 27858342 Physiologically Based Pharmacokinetic (PBPK) Modeling of Pitavastatin and Atorvastatin to Predict Drug-Drug Interactions (DDIs). 2017 Aug 3
9 28479356 Quantitative Analysis of Complex Drug-Drug Interactions Between Repaglinide and Cyclosporin A/Gemfibrozil Using Physiologically Based Pharmacokinetic Models With In Vitro Transporter/Enzyme Inhibition Data. 2017 Sep 2
10 28535976 Organic Anion-Transporting Polypeptide and Efflux Transporter-Mediated Hepatic Uptake and Biliary Excretion of Cilostazol and Its Metabolites in Rats and Humans. 2017 Sep 1
11 26353895 Drug-Drug Interactions with the NS3/4A Protease Inhibitor Simeprevir. 2016 Feb 1
12 27447836 Metabolomic and Genome-wide Association Studies Reveal Potential Endogenous Biomarkers for OATP1B1. 2016 Nov 2
13 27603548 Pre-incubation with cyclosporine A potentiates its inhibitory effects on pitavastatin uptake mediated by recombinantly expressed cynomolgus monkey hepatic organic anion transporting polypeptide. 2016 Nov 1
14 25414411 Investigation of the impact of substrate selection on in vitro organic anion transporting polypeptide 1B1 inhibition profiles for the prediction of drug-drug interactions. 2015 Feb 2
15 25522788 Physiology-based pharmacokinetics of caspofungin for adults and paediatrics. 2015 Jun 2
16 23886114 In vitro OATP1B1 and OATP1B3 inhibition is associated with observations of benign clinical unconjugated hyperbilirubinemia. 2014 Mar 1
17 24623479 Reduced physiologically-based pharmacokinetic model of repaglinide: impact of OATP1B1 and CYP2C8 genotype and source of in vitro data on the prediction of drug-drug interaction risk. 2014 Sep 1
18 23440887 Long-lasting inhibitory effects of saquinavir and ritonavir on OATP1B1-mediated uptake. 2013 Sep 2
19 22240838 Long-lasting inhibitory effects of cyclosporin A, but not tacrolimus, on OATP1B1- and OATP1B3-mediated uptake. 2012 8
20 21245207 Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake. 2011 Mar 1
21 21297316 Clinical importance of OATP1B1 and OATP1B3 in drug-drug interactions. 2011 Jun 1
22 21430235 Role of organic anion-transporting polypeptides for cellular mesalazine (5-aminosalicylic acid) uptake. 2011 Jun 1
23 20519340 Cyclosporine A, but not tacrolimus, shows relevant inhibition of organic anion-transporting protein 1B1-mediated transport of atorvastatin. 2010 Sep 1
24 20540932 Fluorescence-based assays for the assessment of drug interaction with the human transporters OATP1B1 and OATP1B3. 2010 Oct 1 1
25 17901929 Multiple inhibition mechanisms and prediction of drug-drug interactions: status of metabolism and transporter models as exemplified by gemfibrozil-drug interactions. 2008 May 1
26 18192894 Pharmacogenetics of cyclosporine in children suggests an age-dependent influence of ABCB1 polymorphisms. 2008 Feb 1
27 17496208 Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil. 2007 Aug 1
28 17178259 Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance. 2006 Dec 4
29 16198658 Cyclosporine markedly raises the plasma concentrations of repaglinide. 2005 Oct 2
30 16316932 Effects of fibrates on human organic anion-transporting polypeptide 1B1-, multidrug resistance protein 2- and P-glycoprotein-mediated transport. 2005 Jul 1
31 16541750 [Incremental effect and mechanism of cyclosporine on blood concentration of statins and statin package insert information in Japan]. 2005 1
32 15289793 Rosuvastatin pharmacokinetics in heart transplant recipients administered an antirejection regimen including cyclosporine. 2004 Aug 2
33 12538813 Inhibition of transporter-mediated hepatic uptake as a mechanism for drug-drug interaction between cerivastatin and cyclosporin A. 2003 Feb 3
34 14530907 Characterization of the transport of the bicyclic peptide phalloidin by human hepatic transport proteins. 2003 Nov 2