Pub. Date : 2005 Oct
PMID : 16198658
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The effect of cyclosporine on repaglinide AUC0-infinity was 42% lower in subjects with the SLCO1B1 521TC genotype than in subjects with the 521TT (reference) genotype (P=.047). | Cyclosporine | solute carrier organic anion transporter family member 1B1 | Homo sapiens |
| 2 | CONCLUSIONS: Cyclosporine raised the plasma concentrations of repaglinide, probably by inhibiting its CYP3A4-catalyzed biotransformation and OATP1B1-mediated hepatic uptake. | Cyclosporine | solute carrier organic anion transporter family member 1B1 | Homo sapiens |