| 1 |
34821075 | Assessment of Pharmacokinetic Interaction Between Gefapixant (MK-7264), a P2X3 Receptor Antagonist, and the OATP1B1 Drug Transporter Substrate Pitavastatin. | 2022 Mar |
1 |
| 2 |
35351775 | Is The Protein-Mediated Uptake Of Drugs By OATPs A Real Phenomenon Or An Artifact? | 2022 Mar 29 |
2 |
| 3 |
30528195 | Effect of OATP1B1 genotypes on plasma concentrations of endogenous OATP1B1 substrates and drugs, and their association in healthy volunteers. | 2019 Feb |
3 |
| 4 |
30652318 | Functional characterization for polymorphic organic anion transporting polypeptides (OATP/SLCO1B1, 1B3, 2B1) of monkeys recombinantly expressed with various OATP probes. | 2019 Feb |
3 |
| 5 |
29666154 | Prediction and Quantification of Hepatic Transporter-Mediated Uptake of Pitavastatin Utilizing a Combination of the Relative Activity Factor Approach and Mechanistic Modeling. | 2018 Jul |
2 |
| 6 |
30260092 | A Strategy to Refine the Phenotyping Approach and Its Implementation to Predict Drug Clearance: A Physiologically Based Pharmacokinetic Simulation Study. | 2018 Dec |
1 |
| 7 |
27426455 | Development of a high-throughput mass spectrometry based analytical method to support an in vitro OATP1B1 inhibition screening assay. | 2016 Aug 15 |
2 |
| 8 |
27603548 | Pre-incubation with cyclosporine A potentiates its inhibitory effects on pitavastatin uptake mediated by recombinantly expressed cynomolgus monkey hepatic organic anion transporting polypeptide. | 2016 Nov |
1 |
| 9 |
27696476 | Radiosynthesis of novel pitavastatin derivative ([18 F]PTV-F1) as a tracer for hepatic OATP using a one-pot synthetic procedure. | 2016 Nov |
4 |
| 10 |
26037524 | PBPK modeling of irbesartan: incorporation of hepatic uptake. | 2015 Nov |
1 |
| 11 |
25138679 | Ursodeoxycholic acid, an inhibitor of hepatocyte nuclear factor 1α, did not increase the systemic exposure of pitavastatin. | 2014 Nov |
1 |
| 12 |
25221728 | Pharmacogenetics of Statin-Induced Myopathy: A Focused Review of the Clinical Translation of Pharmacokinetic Genetic Variants. | 2014 Apr 23 |
1 |
| 13 |
23007012 | Impact of ABCC2, ABCG2 and SLCO1B1 polymorphisms on the pharmacokinetics of pitavastatin in humans. | 2013 |
2 |
| 14 |
23556337 | CYP2C9*3(1075A > C), ABCB1 and SLCO1B1 genetic polymorphisms and gender are determinants of inter-subject variability in pitavastatin pharmacokinetics. | 2013 Mar |
2 |
| 15 |
23625433 | Effect of pitavastatin in different SLCO1B1 backgrounds on repaglinide pharmacokinetics and pharmacodynamics in healthy Chinese males. | 2013 May |
3 |
| 16 |
21884024 | The role of OATP1B1 and BCRP in pharmacokinetics and DDI of novel statins. | 2012 Oct |
5 |
| 17 |
22022768 | Statin-induced myotoxicity: pharmacokinetic differences among statins and the risk of rhabdomyolysis, with particular reference to pitavastatin. | 2012 Mar |
1 |
| 18 |
22077103 | Effects of the SLCO1B1*15 allele on the pharmacokinetics of pitavastatin. | 2012 May |
8 |
| 19 |
23082789 | Characterization of organic anion transporting polypeptide (OATP) expression and its functional contribution to the uptake of substrates in human hepatocytes. | 2012 Dec 3 |
4 |
| 20 |
20946088 | Differential effect of genetic variants of Na(+)-taurocholate co-transporting polypeptide (NTCP) and organic anion-transporting polypeptide 1B1 (OATP1B1) on the uptake of HMG-CoA reductase inhibitors. | 2011 Jan |
3 |
| 21 |
20175818 | OATP1B1 388A>G polymorphism and pharmacokinetics of pitavastatin in Chinese healthy volunteers. | 2010 Feb |
3 |
| 22 |
18408565 | The effect of SLCO1B1*15 on the disposition of pravastatin and pitavastatin is substrate dependent: the contribution of transporting activity changes by SLCO1B1*15. | 2008 May |
17 |
| 23 |
17460607 | SLCO1B1 (OATP1B1, an uptake transporter) and ABCG2 (BCRP, an efflux transporter) variant alleles and pharmacokinetics of pitavastatin in healthy volunteers. | 2007 Nov |
2 |
| 24 |
16595711 | Drug-drug interaction between pitavastatin and various drugs via OATP1B1. | 2006 Jul |
7 |
| 25 |
15955871 | Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin. | 2005 Sep |
4 |
| 26 |
16198653 | Effect of OATP1B1 (SLCO1B1) variant alleles on the pharmacokinetics of pitavastatin in healthy volunteers. | 2005 Oct |
4 |
| 27 |
16259759 | Transporter-mediated influx and efflux mechanisms of pitavastatin, a new inhibitor of HMG-CoA reductase. | 2005 Oct |
1 |
| 28 |
15159445 | Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the hepatic uptake of pitavastatin in humans. | 2004 Oct |
8 |
| 29 |
15344842 | Metabolic stability and uptake by human hepatocytes of pitavastatin, a new inhibitor of HMG-CoA reductase. | 2004 |
4 |