Title : A Strategy to Refine the Phenotyping Approach and Its Implementation to Predict Drug Clearance: A Physiologically Based Pharmacokinetic Simulation Study.

Pub. Date : 2018 Dec

PMID : 30260092






1 Functional Relationships(s)
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1 The clearance of atorvastatin and repaglinide had a strong correlation (r2 = 0.70 and 0.63, respectively) with that of pitavastatin (a SLCO1B1 probe). pitavastatin solute carrier organic anion transporter family member 1B1 Homo sapiens