| 1 |
34403130 | Pharmacogenomics of statins: lipid response and other outcomes in Brazilian cohorts. | 2022 Feb |
1 |
| 2 |
34887219 | Atorvastatin-associated rhabdomyolysis in a patient with a novel variant of the SLCO1B1 gene: A case report. | 2022 Jan-Feb |
1 |
| 3 |
33805706 | SLCO1B1 Phenotype and CYP3A5 Polymorphism Significantly Affect Atorvastatin Bioavailability. | 2021 Mar 13 |
4 |
| 4 |
32281059 | Influence of Drug-Drug Interactions on the Pharmacokinetics of Atorvastatin and Its Major Active Metabolite ortho-OH-Atorvastatin in Aging People Living with HIV. | 2020 Aug |
1 |
| 5 |
32453264 | Association of SLCO1B1 c.521T>C (rs4149056) with discontinuation of atorvastatin due to statin-associated muscle symptoms. | 2020 Dec |
5 |
| 6 |
32463566 | Systemic Lupus Erythematosus Activity Affects the Sinusoidal Uptake Transporter OATP1B1 Evaluated by the Pharmacokinetics of Atorvastatin. | 2020 Nov |
3 |
| 7 |
33027917 | The Association of 3-Hydroxy-3-Methylglutaryl-CoA Reductase, Apolipoprotein E, and Solute Carrier Organic Anion Genetic Variants with Atorvastatin Response among Jordanian Patients with Type 2 Diabetes. | 2020 Oct 5 |
3 |
| 8 |
29405807 | Interaction of deoxyschizandrin and schizandrin B with liver uptake transporters OATP1B1 and OATP1B3. | 2019 Feb |
2 |
| 9 |
29944058 | Modulation of transporter activity of OATP1B1 and OATP1B3 by the major active components of Radix Ophiopogonis. | 2019 Oct |
1 |
| 10 |
30528195 | Effect of OATP1B1 genotypes on plasma concentrations of endogenous OATP1B1 substrates and drugs, and their association in healthy volunteers. | 2019 Feb |
3 |
| 11 |
30652318 | Functional characterization for polymorphic organic anion transporting polypeptides (OATP/SLCO1B1, 1B3, 2B1) of monkeys recombinantly expressed with various OATP probes. | 2019 Feb |
1 |
| 12 |
31298164 | Association of SLCO1B1 and ABCB1 Genetic Variants with Atorvastatin-induced Myopathy in Patients with Acute Ischemic Stroke. | 2019 |
1 |
| 13 |
28653144 | Explaining Ethnic Variability of Transporter Substrate Pharmacokinetics in Healthy Asian and Caucasian Subjects with Allele Frequencies of OATP1B1 and BCRP: A Mechanistic Modeling Analysis. | 2018 Apr |
1 |
| 14 |
29034773 | Substrate-dependent effects of molecular-targeted anticancer agents on activity of organic anion transporting polypeptide 1B1. | 2018 Oct |
1 |
| 15 |
30260092 | A Strategy to Refine the Phenotyping Approach and Its Implementation to Predict Drug Clearance: A Physiologically Based Pharmacokinetic Simulation Study. | 2018 Dec |
1 |
| 16 |
30569848 | Association of SLCO1B1 Polymorphisms and Atorvastatin Safety and Efficacy: A Meta-analysis. | 2018 |
5 |
| 17 |
28069721 | Specific Inhibition of the Distribution of Lobeglitazone to the Liver by Atorvastatin in Rats: Evidence for a Rat Organic Anion Transporting Polypeptide 1B2-Mediated Interaction in Hepatic Transport. | 2017 Mar |
2 |
| 18 |
28435225 | Association of genetic variations with pharmacokinetics and lipid-lowering response to atorvastatin in healthy Korean subjects. | 2017 |
2 |
| 19 |
29039339 | Effects of two functionally important SLCO1B1 gene polymorphisms on pharmacokinetics of atorvastatin. | 2017 Jul |
3 |
| 20 |
29441875 | Influence of SLCO1B1 polymorphisms on atorvastatin efficacy and safety in Macedonian subjects. | 2017 May 1 |
8 |
| 21 |
29442027 | The effect of SLCO1B1 polymorphism on the pharmacokinetics of atorvastatin and 2-hydroxyatorvastatin in healthy Chinese people. | 2017 Jun 1 |
5 |
| 22 |
26857559 | A pharmacogenetic pilot study reveals MTHFR, DRD3, and MDR1 polymorphisms as biomarker candidates for slow atorvastatin metabolizers. | 2016 Feb 8 |
1 |
| 23 |
26932749 | Genetic determinants of lipid-lowering response to atorvastatin therapy in an Indian population. | 2016 Jun |
2 |
| 24 |
27296832 | ABCB1 polymorphism is associated with atorvastatin-induced liver injury in Japanese population. | 2016 Jun 13 |
1 |
| 25 |
27624558 | The enhanced atorvastatin hepatotoxicity in diabetic rats was partly attributed to the upregulated hepatic Cyp3a and SLCO1B1. | 2016 Sep 14 |
2 |
| 26 |
27631194 | Mapping SLCO1B1 Genetic Variation for Global Precision Medicine in Understudied Regions in Africa: A Focus on Zulu and Cape Admixed Populations. | 2016 Sep |
1 |
| 27 |
25673568 | Impact of ABCG2 and SLCO1B1 polymorphisms on pharmacokinetics of rosuvastatin, atorvastatin and simvastatin acid in Caucasian and Asian subjects: a class effect? | 2015 Mar |
2 |
| 28 |
26086347 | ABCG2 gene polymorphisms as risk factors for atorvastatin adverse reactions: a case-control study. | 2015 Jul |
1 |
| 29 |
26334272 | SLCO1B1 c.388A>G Polymorphism Is Associated with HDL-C Levels in Response to Atorvastatin in Chilean Individuals. | 2015 Aug 31 |
3 |
| 30 |
26373210 | Effects of single nucleotide polymorphisms and haplotypes of the SLCO1B1 gene on the pharmacokinetic profile of atorvastatin in healthy Macedonian volunteers. | 2015 Jul |
4 |
| 31 |
26426900 | Inhibitory Effects of Green Tea and (-)-Epigallocatechin Gallate on Transport by OATP1B1, OATP1B3, OCT1, OCT2, MATE1, MATE2-K and P-Glycoprotein. | 2015 |
1 |
| 32 |
24668570 | No impact of SLCO1B1 521T>C, 388A>G and 411G>A polymorphisms on response to statin therapy in the Greek population. | 2014 Jul |
6 |
| 33 |
24799396 | Hepatic uptake of atorvastatin: influence of variability in transporter expression on uptake clearance and drug-drug interactions. | 2014 Jul |
1 |
| 34 |
25563221 | Genetically guided statin therapy on statin perceptions, adherence, and cholesterol lowering: a pilot implementation study in primary care patients. | 2014 Mar 27 |
1 |
| 35 |
23263738 | Lack of association between SLCO1B1 polymorphism and the lipid-lowering effects of atorvastatin and simvastatin in Chinese individuals. | 2013 Jun |
1 |
| 36 |
23311897 | Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1. | 2013 |
6 |
| 37 |
23361102 | Impact of OATP1B1, MDR1, and CYP3A4 expression in liver and intestine on interpatient pharmacokinetic variability of atorvastatin in obese subjects. | 2013 Mar |
4 |
| 38 |
23677857 | Do MDR1 and SLCO1B1 polymorphisms influence the therapeutic response to atorvastatin? A study on a cohort of Egyptian patients with hypercholesterolemia. | 2013 Oct |
3 |
| 39 |
23822632 | An integrated in vitro model for simultaneous assessment of drug uptake, metabolism, and efflux. | 2013 Aug 5 |
1 |
| 40 |
23876492 | Clinical and pharmacogenetic predictors of circulating atorvastatin and rosuvastatin concentrations in routine clinical care. | 2013 Aug |
1 |
| 41 |
21243006 | Differential effect of the rs4149056 variant in SLCO1B1 on myopathy associated with simvastatin and atorvastatin. | 2012 Jun |
2 |
| 42 |
21928084 | SLCO1B1 haplotypes are not associated with atorvastatin-induced myalgia in Brazilian patients with familial hypercholesterolemia. | 2012 Mar |
3 |
| 43 |
22394605 | Inhibition of hepatic uptake transporters by flavonoids. | 2012 May 12 |
4 |
| 44 |
22524173 | Role of genetic factors in statins side-effects. | 2012 Sep |
1 |
| 45 |
22541068 | Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. | 2012 May 24 |
1 |
| 46 |
22789711 | Evaluation of organic anion-transporting polypeptide 1B1 and CYP3A4 activities in primary human hepatocytes and HepaRG cells cultured in a dynamic three-dimensional bioreactor system. | 2012 Oct |
2 |
| 47 |
23183505 | Possible gene-gender interaction between the SLCO1B1 polymorphism and statin treatment efficacy. | 2012 |
1 |
| 48 |
20946088 | Differential effect of genetic variants of Na(+)-taurocholate co-transporting polypeptide (NTCP) and organic anion-transporting polypeptide 1B1 (OATP1B1) on the uptake of HMG-CoA reductase inhibitors. | 2011 Jan |
2 |
| 49 |
21297370 | [Genetic marker of statin-induced rhabdomyolysis]. | 2011 Feb |
1 |
| 50 |
22016628 | Pharmacogenetics of OATP transporters reveals that SLCO1B1 c.388A>G variant is determinant of increased atorvastatin response. | 2011 |
3 |