Pub. Date : 2019 Feb
PMID : 29405807
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Atorvastatin and rifampicin could inhibit the uptake of deoxyschizandrin and schizandrin B mediated by OATP1B1. | Atorvastatin | solute carrier organic anion transporter family member 1B1 | Homo sapiens |
| 2 | Intriguingly, both deoxyschizandrin and schizandrin B significantly promoted the uptake of atorvastatin (with EC50 of 50.58 +- 8.08 and 24.70 +- 5.82 microM, respectively) and rosuvastatin (with EC50 of 13.46 +- 2.70 and 8.99 +- 4.73 microM, respectively) mediated by OATP1B1. | Atorvastatin | solute carrier organic anion transporter family member 1B1 | Homo sapiens |