Cisplatin

BCL2 apoptosis regulator ; Homo sapiens







433 Article(s)
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151 26575528 Synergistic anticancer effects of cisplatin and histone deacetylase inhibitors (SAHA and TSA) on cholangiocarcinoma cell lines. 2016 Jan 1
152 26692364 Phloretin exhibits an anticancer effect and enhances the anticancer ability of cisplatin on non-small cell lung cancer cell lines by regulating expression of apoptotic pathways and matrix metalloproteinases. 2016 Feb 1
153 26718738 Flap endonuclease 1 silencing is associated with increasing the cisplatin sensitivity of SGC‑7901 gastric cancer cells. 2016 Jan 2
154 26729257 Morphine, a potential antagonist of cisplatin cytotoxicity, inhibits cisplatin-induced apoptosis and suppression of tumor growth in nasopharyngeal carcinoma xenografts. 2016 Jan 5 1
155 26744308 MiR-125b Functions as a Tumor Suppressor and Enhances Chemosensitivity to Cisplatin in Osteosarcoma. 2016 Dec 1
156 26966728 Upregulated expression of BCL2, MCM7, and CCNE1 indicate cisplatin-resistance in the set of two human bladder cancer cell lines: T24 cisplatin sensitive and T24R2 cisplatin resistant bladder cancer cell lines. 2016 Jan 5
157 26996126 Cisplatin-induced apoptosis in non-small-cell lung cancer cells is dependent on Bax- and Bak-induction pathway and synergistically activated by BH3-mimetic ABT-263 in p53 wild-type and mutant cells. 2016 Apr 29 1
158 27029054 Exosomes derived from gefitinib-treated EGFR-mutant lung cancer cells alter cisplatin sensitivity via up-regulating autophagy. 2016 Apr 26 1
159 27044825 Soluble CD40 ligands sensitize the epithelial ovarian cancer cells to cisplatin treatment. 2016 Apr 1
160 27082738 Docetaxel induces Bcl-2- and pro-apoptotic caspase-independent death of human prostate cancer DU145 cells. 2016 Jun 1
161 27083050 Reduction of microRNA-184 by E6 oncoprotein confers cisplatin resistance in lung cancer via increasing Bcl-2. 2016 May 31 4
162 27105491 The La protein counteracts cisplatin-induced cell death by stimulating protein synthesis of anti-apoptotic factor Bcl2. 2016 May 17 5
163 27110775 Smad3 Sensitizes Hepatocelluar Carcinoma Cells to Cisplatin by Repressing Phosphorylation of AKT. 2016 Apr 22 1
164 27138804 MCL-1 is the key target of adjuvant chemotherapy to reverse the cisplatin-resistance in NSCLC. 2016 Aug 10 1
165 27177238 Berberine in combination with cisplatin suppresses breast cancer cell growth through induction of DNA breaks and caspase-3-dependent apoptosis. 2016 Jul 1
166 27226901 Cdk2 phosphorylation of Bcl-xL after stress converts it to a pro-apoptotic protein mimicking Bax/Bak. 2016 1
167 27419628 Glutamine deprivation plus BPTES alters etoposide- and cisplatin-induced apoptosis in triple negative breast cancer cells. 2016 Aug 23 1
168 27484725 Co-expression of ING4 and P53 enhances hypopharyngeal cancer chemosensitivity to cisplatin in vivo. 2016 Sep 2
169 27494891 Analysis of the chemotherapeutic effects of a propadiene compound on malignant ovarian cancer cells. 2016 Aug 30 1
170 27588477 eIF4E promotes tumorigenesis and modulates chemosensitivity to cisplatin in esophageal squamous cell carcinoma. 2016 Oct 11 1
171 27591926 Cisplatin and resveratrol induce apoptosis and autophagy following oxidative stress in malignant mesothelioma cells. 2016 Nov 1
172 27748803 ABT737 reverses cisplatin resistance by regulating ER-mitochondria Ca2+ signal transduction in human ovarian cancer cells. 2016 Dec 7
173 27895723 Cisplatin-induced regulation of signal transduction pathways and transcription factors in p53-mutated subclone variants of hepatoma cells: Potential application for therapeutic targeting. 2016 Nov 2
174 29714913 [Induction of Apoptosis of Human Cisplatin-resistance Lung Cancer Cells with MPPa-photodynamic Therapy]. 2016 Aug 2
175 29797935 [Investigation of CXCR4 mediated chemoresistance in nasopharyngeal carcinoma cell line CNE2]. 2016 Jun 5 1
176 25348020 TXNL1 induces apoptosis in cisplatin resistant human gastric cancer cell lines. 2015 1
177 25348361 DNA-PKcs deficiency sensitizes the human hepatoma HepG2 cells to cisplatin and 5-fluorouracil through suppression of the PI3K/Akt/NF-κB pathway. 2015 Jan 1
178 25405848 Downregulation of osteopontin enhances the sensitivity of glioma U251 cells to temozolomide and cisplatin by targeting the NF-κB/Bcl‑2 pathway. 2015 Mar 1
179 25492481 Involvement of miR-143 in cisplatin resistance of gastric cancer cells via targeting IGF1R and BCL2. 2015 Apr 4
180 25499851 MnSOD overexpression confers cisplatin resistance in lung adenocarcinoma via the NF-κB/Snail/Bcl-2 pathway. 2015 Feb 4
181 25582599 The combination of thioxodihydroquinazolinones and platinum drugs reverses platinum resistance in tumor cells by inducing mitochondrial apoptosis independent of Bax and Bak. 2015 Feb 15 1
182 25604244 TTP mediates cisplatin-induced apoptosis of head and neck cancer cells by down-regulating the expression of Bcl-2. 2015 Jun 7
183 25770930 Combination of chrysin and cisplatin promotes the apoptosis of Hep G2 cells by up-regulating p53. 2015 May 5 1
184 25823945 Small-molecule inhibitor of Bcl-2 (TW-37) suppresses growth and enhances cisplatin-induced apoptosis in ovarian cancer cells. 2015 Feb 20 1
185 25885284 Chemoresistance is associated with increased cytoprotective autophagy and diminished apoptosis in bladder cancer cells treated with the BH3 mimetic (-)-Gossypol (AT-101). 2015 Apr 7 1
186 25894537 Loss of α(E)-catenin promotes Fas mediated apoptosis in tubular epithelial cells. 2015 Jul 3
187 25904702 Melatonin pretreatment of human adipose tissue-derived mesenchymal stromal cells enhances their prosurvival and protective effects on human kidney cells. 2015 Jun 15 1
188 25936772 ABT737 enhances cholangiocarcinoma sensitivity to cisplatin through regulation of mitochondrial dynamics. 2015 Jul 1 2
189 26055133 Protective effect of Artemisia asiatica (Pamp.) Nakai ex Kitam ethanol extract against cisplatin-induced apoptosis of human HaCaT keratinocytes: Involvement of NF-kappa B- and Bcl-2-controlled mitochondrial signaling. 2015 Jun 1 2
190 26089640 Small-molecule BH3 mimetic and pan-Bcl-2 inhibitor AT-101 enhances the antitumor efficacy of cisplatin through inhibition of APE1 repair and redox activity in non-small-cell lung cancer. 2015 1
191 26151347 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells. 2015 Oct 2
192 26171069 Synergistic effects of cisplatin and proteasome inhibitor bortezomib on human bladder cancer cells. 2015 Jul 3
193 26310353 Butein sensitizes HeLa cells to cisplatin through the AKT and ERK/p38 MAPK pathways by targeting FoxO3a. 2015 Oct 1
194 26313152 IL-6 signaling contributes to cisplatin resistance in non-small cell lung cancer via the up-regulation of anti-apoptotic and DNA repair associated molecules. 2015 Sep 29 1
195 26314326 Resveratrol enhanced anticancer effects of cisplatin on non-small cell lung cancer cell lines by inducing mitochondrial dysfunction and cell apoptosis. 2015 Oct 1
196 26323558 MiR-873 acts as a novel sensitizer of glioma cells to cisplatin by targeting Bcl-2. 2015 Oct 5
197 26366416 Lysophosphatidic Acid Inhibits Apoptosis Induced by Cisplatin in Cervical Cancer Cells. 2015 1
198 26396928 Synergistic effect of allyl isothiocyanate (AITC) on cisplatin efficacy in vitro and in vivo. 2015 1
199 26403741 [Overexpression of STOML-2 inhibits apoptosis of human cervical squamous carcinoma Siha cells in vitro]. 2015 Aug 1
200 26474854 Bcl-2 confers survival in cisplatin treated cervical cancer cells: circumventing cisplatin dose-dependent toxicity and resistance. 2015 Oct 16 7