Tetradecanoylphorbol Acetate

BCL2 apoptosis regulator ; Homo sapiens







36 Article(s)
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1 32640883 Combination of diethyldithiocarbamate with 12-O-tetradecanoyl phorbol-13-acetate inhibits the growth of human myeloid leukemia HL-60 cells in vitro and in xenograft model. 2020 Oct 1
2 27520485 Epigenetic blockade of neoplastic transformation by bromodomain and extra-terminal (BET) domain protein inhibitor JQ-1. 2016 Oct 1 1
3 25310083 N‑acetyl‑L‑cysteine reduces arsenite‑induced cytotoxicity through chelation in U937 monocytes and macrophages. 2014 Dec 1
4 21901143 Upregulation of cellular Bcl-2 by the KSHV encoded RTA promotes virion production. 2011 1
5 16761109 Inducer-and cell type-specific regulation of antiapoptotic MCL1 in myeloid leukemia and multiple myeloma cells exposed to differentiation-inducing or microtubule-disrupting agents. 2006 Aug 2
6 15748703 Mitochondrial-dependent, reactive oxygen species-independent apoptosis by myricetin: roles of protein kinase C, cytochrome c, and caspase cascade. 2005 Mar 15 1
7 16277846 [JWA gene in regulating committed differentiation of HL-60 cells induced by ATRA, Ara-C and TPA]. 2005 Oct 1
8 12684678 Inactive caspase 3 activates Akt in human leukemia cells susceptible or resistant to apoptosis induced by phorbol ester. 2003 May 2
9 12890888 Possible involvement of both endoplasmic reticulum-and mitochondria-dependent pathways in thapsigargin-induced apoptosis in human neuroblastoma SH-SY5Y cells. 2003 Jul 1
10 12046067 Induction of apoptosis by TPA and VP-16 is through translocation of TR3. 2002 Jun 1
11 11476900 Effect of phorbol ester and calcium ionophore on human thymocytes. 2001 Aug 1
12 10627292 A conserved AU-rich element in the 3' untranslated region of bcl-2 mRNA is endowed with a destabilizing function that is involved in bcl-2 down-regulation during apoptosis. 2000 Jan 2
13 10961874 Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells. 2000 Sep 1 1
14 11095401 Survival mechanisms induced by 12-O-tetradecanoylphorbol-13-acetate in normal human melanocytes include inhibition of apoptosis and increased Bcl-2 expression. 2000 Oct 3
15 9880563 Regulation of MCL1 through a serum response factor/Elk-1-mediated mechanism links expression of a viability-promoting member of the BCL2 family to the induction of hematopoietic cell differentiation. 1999 Jan 15 2
16 10381626 Selective inhibition of apoptosis by TPA-induced differentiation of U937 leukemic cells. 1999 Apr 1
17 10400418 Mitogen-activated protein kinase pathway is dispensable for microtubule-active drug-induced Raf-1/Bcl-2 phosphorylation and apoptosis in leukemia cells. 1999 Jul 1
18 9460707 Nitric oxide donor-induced p53-sensitive cell death is enhanced by Bcl-2 reduction in human neuroblastoma cells. 1998 Jan 1
19 9879997 Induction of apoptosis in breast cancer cells by TPA. 1998 Dec 3 1
20 9295281 Protein kinase CbetaII activation by 1-beta-D-arabinofuranosylcytosine is antagonistic to stimulation of apoptosis and Bcl-2alpha down-regulation. 1997 Sep 19 3
21 9317114 B cell receptor cross-linking prevents Fas-induced cell death by inactivating the IL-1 beta-converting enzyme protease and regulating Bcl-2/Bcl-x expression. 1997 Oct 1 1
22 9364213 bcl-2 enhancement of malignant transformation in mouse epidermal JB6 cells. 1997 Oct 3
23 8633098 BCL2 regulates neural differentiation. 1996 Apr 30 1
24 8635587 Suppression of bcl-2 gene expression by sphingosine in the apoptosis of human leukemic HL-60 cells during phorbol ester-induced terminal differentiation. 1996 Jan 29 1
25 8666983 Regulation of Bcl-2 protein expression in human neuroblastoma SH-SY5Y cells: positive and negative effects of protein kinases C and A, respectively. 1996 Jul 2
26 8798441 CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas. 1996 Sep 13 2
27 8816467 Induction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation and rescue from apoptosis. 1996 Oct 1
28 8830674 Co-ordinated downregulation of bcl-2 and bax expression during granulocytic and macrophage-like differentiation of the HL60 promyelocytic leukaemia cell line. 1996 Oct 7 2
29 7671257 Overexpression of bcl-2 protects prostate cancer cells from apoptosis in vitro and confers resistance to androgen depletion in vivo. 1995 Oct 1 1
30 7747803 Discordant expression of Bcl-x and Bcl-2 by keratinocytes in vitro and psoriatic keratinocytes in vivo. 1995 May 1
31 7795258 Human interleukin-3 receptor modulates bcl-2 mRNA and protein levels through protein kinase C in TF-1 cells. 1995 Jul 1 2
32 7847852 Increased resistance to apoptosis associated with HL-60 myeloid differentiation status. 1994 Sep-Oct 1
33 8019487 Studies on bcl-2 protein in cultured lymphoid cells. 1994 Feb 1
34 8402688 Regulation of Bcl-2 oncoprotein levels with differentiation of human neuroblastoma cells. 1993 Oct 15 1
35 1375120 Growth- and differentiation-associated expression of bcl-2 in B-chronic lymphocytic leukemia cells. 1992 Jun 1 2
36 2011401 Phorbol ester-mediated inhibition of growth and regulation of proto-oncogene expression in the human T cell leukemia line JURKAT. 1991 Mar 2