Title : B cell receptor cross-linking prevents Fas-induced cell death by inactivating the IL-1 beta-converting enzyme protease and regulating Bcl-2/Bcl-x expression.

Pub. Date : 1997 Oct 1

PMID : 9317114






1 Functional Relationships(s)
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1 In this system, Fas ligation also triggers Bcl-2/Bcl-x down-regulation, an effect inhibited by sIgG cross-linking, the cysteine protease inhibitor acetyl-Tyr-Val-Ala-Asp-chloromethyl ketone, and PMA treatment. Tetradecanoylphorbol Acetate BCL2 apoptosis regulator Homo sapiens