Tyrosine

MPL proto-oncogene, thrombopoietin receptor ; Homo sapiens







26 Article(s)
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1 29288169 Defining the requirements for the pathogenic interaction between mutant calreticulin and MPL in MPN. 2018 Feb 15 1
2 26919114 MPL W515L expression induces TGFβ secretion and leads to an increase in chemokinesis via phosphorylation of THOC5. 2016 Mar 8 2
3 27222706 Tyrosine 625 plays a key role and cooperates with tyrosine 630 in MPL W515L-induced signaling and myeloproliferative neoplasms. 2016 3
4 26140605 TPO-Induced Metabolic Reprogramming Drives Liver Metastasis of Colorectal Cancer CD110+ Tumor-Initiating Cells. 2015 Jul 2 1
5 26337118 The adsorption of allergoids and 3-O-desacyl-4'-monophosphoryl lipid A (MPL®) to microcrystalline tyrosine (MCT) in formulations for use in allergy immunotherapy. 2015 Nov 3
6 24070902 Top-down motif engineering of a cytokine receptor for directing ex vivo expansion of hematopoietic stem cells. 2013 Dec 1
7 19996410 Induction of myeloproliferative disorder and myelofibrosis by thrombopoietin receptor W515 mutants is mediated by cytosolic tyrosine 112 of the receptor. 2010 Feb 4 1
8 17034029 Congenital amegakaryocytic thrombocytopenia--report of a new c-mpl gene missense mutation. 2007 Mar 1
9 15001470 Induction of megakaryocytopoiesis and thrombocytopoiesis by JTZ-132, a novel small molecule with thrombopoietin mimetic activities. 2004 Jul 1 1
10 11784712 Cloning and characterization of a family of proteins associated with Mpl. 2002 Mar 15 1
11 11402314 Role of Gab proteins in phosphatidylinositol 3-kinase activation by thrombopoietin (Tpo). 2001 Apr 26 2
12 11421893 A well-tolerated grass pollen-specific allergy vaccine containing a novel adjuvant, monophosphoryl lipid A, reduces allergic symptoms after only four preseasonal injections. 2001 Jun 1
13 10651727 Marked heterogeneity in protein levels and functional integrity of the thrombopoietin receptor c-mpl in polycythaemia vera. 2000 Jan 1
14 10918061 A structure-function analysis of serine/threonine phosphorylation of the thrombopoietin receptor, c-Mpl. 2000 Oct 13 1
15 10068651 Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors. 1999 Mar 15 3
16 10224114 Thrombopoietin signal transduction requires functional JAK2, not TYK2. 1999 May 7 4
17 9600081 Thrombopoietin induces tyrosine phosphorylation of a common beta subunit of GM-CSF receptor and its association with Stat5 in TF-1/TPO cells. 1998 May 8 1
18 9766506 Effects of thrombopoietin, interleukin-3 and the kinase inhibitor K-252a on growth and polyploidization of the megakaryocytic cell line M-07e. 1998 Oct 6
19 11012184 The effect of MGDF on platelet function and thrombosis in animal models. 1998 1
20 8555464 Thrombopoietin induces tyrosine phosphorylation of Stat3 and Stat5 in human blood platelets. 1996 Jan 15 1
21 8695851 p120c-cbl is present in human blood platelets and is differentially involved in signaling by thrombopoietin and thrombin. 1996 Aug 15 2
22 8843545 Thrombopoietin modulates platelet activation in vitro through protein-tyrosine phosphorylation. 1996 Jul 1
23 8898102 Functional analysis of the cytoplasmic domain of the human Mpl receptor for tyrosine-phosphorylation of the signaling molecules, proliferation and differentiation. 1996 Oct 21 1
24 8943867 Crkl is constitutively tyrosine phosphorylated in platelets from chronic myelogenous leukemia patients and inducibly phosphorylated in normal platelets stimulated by thrombopoietin. 1996 Dec 1 1
25 8950973 Discrete protein interactions with the Grb2/c-Cbl complex in SCF- and TPO-mediated myeloid cell proliferation. 1996 Nov 21 2
26 7492761 Regulation of platelet activation in vitro by the c-Mpl ligand, thrombopoietin. 1995 Dec 1 1