Title : Top-down motif engineering of a cytokine receptor for directing ex vivo expansion of hematopoietic stem cells.

Pub. Date : 2013 Dec

PMID : 24070902






1 Functional Relationships(s)
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1 In this study, we engineered a tyrosine motif located in the intracellular domain of S-Mpl based on a top-down approach in order to change the signaling properties of the chimera. Tyrosine MPL proto-oncogene, thrombopoietin receptor Homo sapiens