Fluorouracil

BCL2 associated X, apoptosis regulator ; Homo sapiens







88 Article(s)
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1 34309458 Quercetin and Luteolin Improve the Anticancer Effects of 5-Fluorouracil in Human Colorectal Adenocarcinoma In Vitro Model: A Mechanistic Insight. 2022 2
2 35154466 Synergistic effects of CP-25 and 5-fluorouracil on the hepatocellular carcinoma in vivo and in vitro through regulating activating mitochondrial pathway. 2022 2
3 35245520 Enhanced in vitro tumoricidal effects of 5-Fluorouracil, thymoquinone, and active vitamin D3 triple therapy against colon cancer cells by attenuating the PI3K/AKT/mTOR pathway. 2022 May 1 1
4 35326689 In Vivo and In Vitro Enhanced Tumoricidal Effects of Metformin, Active Vitamin D3, and 5-Fluorouracil Triple Therapy against Colon Cancer by Modulating the PI3K/Akt/PTEN/mTOR Network. 2022 Mar 17 1
5 30990333 Inhibitory effects and molecular mechanisms of pentagalloyl glucose in combination with 5-FU on aggressive phenotypes of HepG2 cells. 2021 Mar 1
6 33460610 Suppression of Nanog inhibited cell migration and increased the sensitivity of colorectal cancer cells to 5-fluorouracil. 2021 Mar 5 1
7 33489855 Celecoxib induces apoptosis through Akt inhibition in 5-fluorouracil-resistant gastric cancer cells. 2021 Jan 1
8 34117917 Anticancer activity of Helicobacter pylori ribosomal protein (HPRP) with iRGD in treatment of colon cancer. 2021 Oct 1
9 34485154 Angelica Polysaccharide Antagonizes 5-FU-Induced Oxidative Stress Injury to Reduce Apoptosis in the Liver Through Nrf2 Pathway. 2021 1
10 34637097 Quercetin potentiates the chemosensitivity of MCF-7 breast cancer cells to 5-fluorouracil. 2021 Dec 3
11 32247004 Protective effect of Andrographolide on 5-Fu induced intestinal mucositis by regulating p38 MAPK signaling pathway. 2020 Jul 1 1
12 32247577 Bcl-2 family proteins, beyond the veil. 2020 1
13 32509181 Emodin reverses 5-Fu resistance in human colorectal cancer via downregulation of PI3K/Akt signaling pathway. 2020 1
14 32689938 Transcriptomic analysis on the effects of melatonin in gastrointestinal carcinomas. 2020 Jul 20 1
15 32975155 Apoptosis pathway in the combined treatment of x-ray and 5-FU-loaded triblock copolymer-coated magnetic nanoparticles. 2020 Aug 1
16 33335403 Superior Effect of the Combination of Carbon-Ion Beam Irradiation and 5-Fluorouracil on Colorectal Cancer Stem Cells in vitro and in vivo. 2020 1
17 30993753 Identification of Nrf2/STAT3 axis in induction of apoptosis through sub-G 1 cell cycle arrest mechanism in HT-29 colon cancer cells. 2019 Aug 1
18 31011291 Large tumor suppressor kinase 2 overexpression attenuates 5-FU-resistance in colorectal cancer via activating the JNK-MIEF1-mitochondrial division pathway. 2019 1
19 31072625 miR-145 Regulates the sensitivity of esophageal squamous cell carcinoma cells to 5-FU via targeting REV3L. 2019 Jul 1
20 31341363 Raddeanin A promotes apoptosis and ameliorates 5-fluorouracil resistance in cholangiocarcinoma cells. 2019 Jul 14 1
21 29054700 Rebamipide suppresses 5-fluorouracil-induced cell death via the activation of Akt/mTOR pathway and regulates the expression of Bcl-2 family proteins. 2018 Feb 1
22 29719602 Leptin-Notch axis impairs 5-fluorouracil effects on pancreatic cancer. 2018 Apr 6 1
23 29738772 Dihydroartemisinin potentiates antitumor activity of 5-fluorouracil against a resistant colorectal cancer cell line. 2018 Jun 27 2
24 29795190 Renal inhibition of miR-181a ameliorates 5-fluorouracil-induced mesangial cell apoptosis and nephrotoxicity. 2018 May 23 1
25 29849804 Bufalin and 5-fluorouracil synergistically induce apoptosis in colorectal cancer cells. 2018 May 2
26 29872316 The synergistic effects of Apatinib combined with cytotoxic chemotherapeutic agents on gastric cancer cells and in a fluorescence imaging gastric cancer xenograft model. 2018 1
27 30056083 Manuka honey synergistically enhances the chemopreventive effect of 5-fluorouracil on human colon cancer cells by inducing oxidative stress and apoptosis, altering metabolic phenotypes and suppressing metastasis ability. 2018 Oct 1
28 30250224 High PGAM5 expression induces chemoresistance by enhancing Bcl-xL-mediated anti-apoptotic signaling and predicts poor prognosis in hepatocellular carcinoma patients. 2018 Sep 24 1
29 31949673 Knockdown of PHGDH potentiates 5-FU cytotoxicity in gastric cancer cells via the Bcl-2/Bax/caspase-3 signaling pathway. 2018 3
30 28178647 Enhancement of TRAIL-induced apoptosis by 5-fluorouracil requires activating Bax and p53 pathways in TRAIL-resistant lung cancers. 2017 Mar 14 3
31 28349835 The role of epithelial cell adhesion molecule N-glycosylation on apoptosis in breast cancer cells. 2017 Mar 1
32 26505786 Combinatorial Effects of Curcumin with an Anti-Neoplastic Agent on Head and Neck Squamous Cell Carcinoma Through the Regulation of EGFR-ERK1/2 and Apoptotic Signaling Pathways. 2016 Jan 11 1
33 26691280 Apoptotic activity of 5-fluorouracil in breast cancer cells transformed by low doses of ionizing α-particle radiation. 2016 Feb 5
34 26892272 Lupeol enhances inhibitory effect of 5-fluorouracil on human gastric carcinoma cells. 2016 May 1
35 27671231 Sanguisorba officinalis L synergistically enhanced 5-fluorouracil cytotoxicity in colorectal cancer cells by promoting a reactive oxygen species-mediated, mitochondria-caspase-dependent apoptotic pathway. 2016 Sep 27 1
36 27693317 Andrographolide reversed 5-FU resistance in human colorectal cancer by elevating BAX expression. 2016 Dec 1 6
37 27924828 rpL3 promotes the apoptosis of p53 mutated lung cancer cells by down-regulating CBS and NFκB upon 5-FU treatment. 2016 Dec 7 1
38 25736303 Resveratrol synergistically augments anti-tumor effect of 5-FU in vitro and in vivo by increasing S-phase arrest and tumor apoptosis. 2015 Dec 1
39 25855960 Histone acetyltransferase PCAF accelerates apoptosis by repressing a GLI1/BCL2/BAX axis in hepatocellular carcinoma. 2015 Apr 9 3
40 26136123 Alpha 7-nicotinic acetylcholine receptor mediates the sensitivity of gastric cancer cells to 5-fluorouracil. 2015 Dec 2
41 24122668 Down-regulation of BAX gene during carcinogenesis and acquisition of resistance to 5-FU in colorectal cancer. 2014 Apr 2
42 24210071 Morphine improved the antitumor effects on MCF-7 cells in combination with 5-Fluorouracil. 2014 Apr 1
43 24515389 Regulatory mechanism of ZNF139 in multi-drug resistance of gastric cancer cells. 2014 Jun 1
44 25087947 Synergistic effects of 5-fluorouracil and gambogenic acid on A549 cells: activation of cell death caused by apoptotic and necroptotic mechanisms via the ROS-mitochondria pathway. 2014 1
45 23076534 Upregulation of periostin prevents P53-mediated apoptosis in SGC-7901 gastric cancer cells. 2013 Feb 1
46 23451189 Curcumin enhances the effect of chemotherapy against colorectal cancer cells by inhibition of NF-κB and Src protein kinase signaling pathways. 2013 1
47 24363520 Cooperative inhibitory effect of sinomenine combined with 5-fluorouracil on esophageal carcinoma. 2013 Dec 7 1
48 22002472 Tanshinone IIA inhibits human hepatocellular carcinoma J5 cell growth by increasing Bax and caspase 3 and decreasing CD31 expression in vivo. 2012 Jan 1
49 22206670 Thymoquinone inhibits growth and augments 5-fluorouracil-induced apoptosis in gastric cancer cells both in vitro and in vivo. 2012 Jan 13 1
50 22366766 EBP50 gene transfection promotes 5-fluorouracil-induced apoptosis in gastric cancer cells through Bax- and Bcl-2-triggered mitochondrial pathways. 2012 May 1