Title : rpL3 promotes the apoptosis of p53 mutated lung cancer cells by down-regulating CBS and NFκB upon 5-FU treatment.

Pub. Date : 2016 Dec 7

PMID : 27924828






1 Functional Relationships(s)
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1 Furthermore, we demonstrate that rpL3 significantly enhances the apoptosis of 5-FU treated Calu-6 cells promoting the overexpression of the pro-apoptotic proteins Bax and the inhibition of the anti-apoptotic protein Bcl-2. Fluorouracil BCL2 associated X, apoptosis regulator Homo sapiens