Cisplatin

BCL2 associated X, apoptosis regulator ; Homo sapiens







235 Article(s)
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201 12599692 [Effect of traditional Chinese medicine compounds Aining on the expression of apoptosis inducing genes of human gastric cancer cell]. 2002 Aug 1
202 11125422 Enhanced sensitivity of bladder cancer cells to tumor necrosis factor related apoptosis inducing ligand mediated apoptosis by cisplatin and carboplatin. 2001 Jan 1
203 11172605 Enhancement of antitumor effect by intratumoral administration of bax gene in combination with anticancer drugs in gastric cancer. 2001 Feb 1
204 11267864 Combination effect of adenovirus-mediated pro-apoptotic bax gene transfer with cisplatin or paclitaxel treatment in ovarian cancer cell lines. 2001 Mar 10
205 11299769 Mechanism of differential sensitivity to cisplatin in nasopharyngeal carcinoma cells. 2001 Jan-Feb 1
206 11313183 The novel trinuclear platinum complex BBR3464 induces a cellular response different from cisplatin. 2001 May 1
207 11340162 Cisplatin induces the proapoptotic conformation of Bak in a deltaMEKK1-dependent manner. 2001 Jun 1
208 11384107 Telomerase activity and p53-dependent apoptosis in ovarian cancer cells. 2001 Jun 1 1
209 11401473 Vitamin C augments chemotherapeutic response of cervical carcinoma HeLa cells by stabilizing P53. 2001 Mar 30 1
210 11497278 Mechanism of growth-inhibitory effect of cisplatin on human pancreatic cancer cells and status of p53 gene. 2001 May-Jun 1
211 11761456 Regulation of p53 target gene expression by cisplatin-induced extracellular signal-regulated kinase. 2001 Nov 1
212 11848465 Restoration of bax in prostate cancer suppresses tumor growth and augments therapeutic cell death induction. 2001 Sep-Oct 1
213 10762058 Enhanced induction of Bax gene expression in H460 and H1299 cells with the combined treatment of cisplatin and adenovirus mediated wt-p53 gene transfer. 2000 Mar 31 2
214 10769693 Enhancement of chemotherapeutic agents induced-apoptosis associated with activation of c-Jun N-terminal kinase 1 and caspase 3 (CPP32) in bax-transfected gastric cancer cells. 2000 Jan-Feb 3
215 10880019 Cre-loxP-mediated bax gene activation reduces growth rate and increases sensitivity to chemotherapeutic agents in human gastric cancer cells. 2000 Jun 1
216 10891529 Theophylline and cisplatin synergize in down regulation of BCL-2 induction of apoptosis in human granulosa cells transformed by a mutated p53 (p53 val135) and Ha-ras oncogene. 2000 Aug 1
217 10974635 Sensitivity to paclitaxel is not related to p53-dependent apoptosis in ovarian cancer cells. 2000 Sep 1
218 11123425 Bax induction activates apoptotic cascade via mitochondrial cytochrome c release and Bax overexpression enhances apoptosis induced by chemotherapeutic agents in DLD-1 colon cancer cells. 2000 Dec 1
219 11175336 Formation of nuclear Bax/p53 complexes is associated with chemotherapy induced apoptosis. 2000 Dec 14 3
220 10024685 Taxol-induced bcl-2 phosphorylation in ovarian cancer cell monolayer and spheroids. 1999 Mar 1
221 10063313 The relationship between cisplatin-induced apoptosis and p53, bcl-2 and bax expression in human lung cancer cells. 1999 Jan 1
222 10080945 STAT-1-independent upregulation of FADD and procaspase-3 and -8 in cancer cells treated with cytotoxic drugs. 1999 Mar 24 1
223 10397248 Cisplatin-induced apoptosis proceeds by caspase-3-dependent and -independent pathways in cisplatin-resistant and -sensitive human ovarian cancer cell lines. 1999 Jul 1 1
224 10446454 Apoptosis-promoting gene (bax) transfer potentiates sensitivity of squamous cell carcinoma to cisplatin in vitro and in vivo. 1999 Sep 9 4
225 9584207 Cisplatin- and paclitaxel-induced apoptosis of ovarian carcinoma cells and the relationship between bax and bak up-regulation and the functional status of p53. 1998 May 1
226 9635829 Expression of p53, Bcl-2 and Bax in cisplatin-induced apoptosis in testicular germ cell tumour cell lines. 1998 May 3
227 9041117 Bax upregulation is an early event in cisplatin-induced apoptosis in human testicular germ-cell tumor cell line NT2, as quantitated by flow cytometry. 1997 Mar 1 1
228 9212237 Mechanism of resistance to cisplatin in a human ovarian-carcinoma cell line selected for resistance to doxorubicin: possible role of p53. 1997 Jul 3 1
229 9306577 Overexpression of bax sensitizes breast cancer MCF-7 cells to cisplatin and etoposide. 1997 1
230 9393748 Galectin-3: a novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family. 1997 Dec 1 1
231 9413185 Mechanism of apoptosis induced by cisplatin and VP-16 in PANC-1 cells. 1997 Sep-Oct 1
232 9494534 Human melanoma cell lines selected in vitro displaying various levels of drug resistance against cisplatin, fotemustine, vindesine or etoposide: modulation of proto-oncogene expression. 1997 Nov-Dec 1
233 9815594 all-trans retinoic acid enhances cisplatin-induced apoptosis in human ovarian adenocarcinoma and in squamous head and neck cancer cells. 1997 Nov 1
234 8564971 Association between cisplatin resistance and mutation of p53 gene and reduced bax expression in ovarian carcinoma cell systems. 1996 Feb 1 3
235 8798452 Bax can antagonize Bcl-XL during etoposide and cisplatin-induced cell death independently of its heterodimerization with Bcl-XL. 1996 Sep 13 3