Genistein

BCL2 associated X, apoptosis regulator ; Homo sapiens







39 Article(s)
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1 33347704 Genistein enhances the effects of L-asparaginase on inducing cell apoptosis in human leukemia cancer HL-60 cells. 2021 May 1
2 31579960 Genistein protects ovarian granulosa cells from oxidative stress via cAMP-PKA signaling. 2020 Feb 1
3 30450837 Genistein inhibits Aβ25-35 -induced SH-SY5Y cell damage by modulating the expression of apoptosis-related proteins and Ca2+ influx through ionotropic glutamate receptors. 2019 Feb 2
4 30618158 Genistein induces apoptosis in vitro and has antitumor activity against human leukemia HL-60 cancer cell xenograft growth in vivo. 2019 Apr 1
5 31360194 Genistein-triggered anticancer activity against liver cancer cell line HepG2 involves ROS generation, mitochondrial apoptosis, G2/M cell cycle arrest and inhibition of cell migration. 2019 Jul 1
6 31438633 Induction of G2/M Cell Cycle Arrest and Apoptosis by Genistein in Human Bladder Cancer T24 Cells through Inhibition of the ROS-Dependent PI3k/Akt Signal Transduction Pathway. 2019 Aug 21 1
7 30003731 Effect of genistein on apoptosis of lung adenocarcinoma A549 cells and expression of apoptosis factors. 2018 May-Jun 1
8 29202800 Genistein induces apoptosis of colon cancer cells by reversal of epithelial-to-mesenchymal via a Notch1/NF-κB/slug/E-cadherin pathway. 2017 Dec 4 1
9 25880142 Genistein induces activation of the mitochondrial apoptosis pathway by inhibiting phosphorylation of Akt in colorectal cancer cells. 2016 1
10 25675448 Genistein induces apoptosis by the inactivation of the IGF-1R/p-Akt signaling pathway in MCF-7 human breast cancer cells. 2015 Mar 2
11 26064333 ATRA and Genistein synergistically inhibit the metastatic potential of human lung adenocarcinoma cells. 2015 1
12 26469967 Caspase-3 feedback loop enhances Bid-induced AIF/endoG and Bak activation in Bax and p53-independent manner. 2015 Oct 15 4
13 26841510 [Cytoprotective Effects of Phytoestrogen Genistein against Cancer Cells]. 2015 Nov-Dec 1
14 24573886 Genistein induces apoptosis and autophagy in human breast MCF-7 cells by modulating the expression of proapoptotic factors and oxidative stress enzymes. 2014 May 1
15 25009600 Genistein inhibits the proliferation and differentiation of MCF-7 and 3T3-L1 cells via the regulation of ERα expression and induction of apoptosis. 2014 Aug 2
16 25128065 Apoptotic effect of genistein on human colon cancer cells via inhibiting the nuclear factor-kappa B (NF-κB) pathway. 2014 Nov 1
17 23999913 Genistein enhances the efficacy of cabazitaxel chemotherapy in metastatic castration-resistant prostate cancer cells. 2013 Nov 2
18 22227334 IGF-I receptor signaling pathway is involved in the neuroprotective effect of genistein in the neuroblastoma SK-N-SH cells. 2012 Feb 29 1
19 22493348 Physiological concentrations of genistein and 17β-estradiol inhibit MDA-MB-231 breast cancer cell growth by increasing BAX/BCL-2 and reducing pERK1/2. 2012 Apr 2
20 19800779 Effects of diverse dietary phytoestrogens on cell growth, cell cycle and apoptosis in estrogen-receptor-positive breast cancer cells. 2010 Sep 1
21 20067268 Genistein suppresses tumor necrosis factor-alpha-induced proliferation via the apoptotic signaling pathway in human aortic smooth muscle cells. 2010 Feb 10 1
22 19732843 Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways. 2009 Dec 2
23 18470428 [Effects of genistein on the expressions of cell apoptosis-related proteins in salivary adenoid cystic carcinoma cell line SACC-83]. 2008 Apr 2
24 18761399 Genistein induces cell apoptosis in MDA-MB-231 breast cancer cells via the mitogen-activated protein kinase pathway. 2008 Oct 1
25 16758967 [Effects of ERK5 MAPK signaling transduction pathway on the inhibition of genistein to breast cancer cells]. 2006 Mar 1
26 15862028 [Effect of apoptosis in human breast cancer cells and its probable mechanisms by genistein]. 2005 Jan 1
27 15896711 Combination of 5-fluorouracil and genistein induces apoptosis synergistically in chemo-resistant cancer cells through the modulation of AMPK and COX-2 signaling pathways. 2005 Jul 1 1
28 16329599 [Effects of genistein on proliferation and apoptosis in HT-29 cells]. 2005 Sep 1
29 15188515 Apoptosis of human primary gastric carcinoma cells induced by genistein. 2004 Jun 15 2
30 15488634 Inhibition of proliferation and induction of apoptosis by genistein in colon cancer HT-29 cells. 2004 Nov 25 1
31 15659824 Proapoptotic potentials of genistein under growth stimulation by estrogen. 2004 Dec 1
32 12948406 [Proliferation inhibition and apoptosis onset in human ovarian carcinoma cell line SKOV3 induced by Genistein]. 2003 Jun 1
33 12963483 Inhibition of the proteasome activity, a novel mechanism associated with the tumor cell apoptosis-inducing ability of genistein. 2003 Sep 15 1
34 14707277 Genistein sensitizes diffuse large cell lymphoma to CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) chemotherapy. 2003 Dec 1
35 12239620 Soy isoflavone genistein modulates cell cycle progression and induces apoptosis in HER-2/neu oncogene expressing human breast epithelial cells. 2002 Oct 1
36 11316564 Genistein, a tyrosine kinase inhibitor, enhanced radiosensitivity in human esophageal cancer cell lines in vitro: possible involvement of inhibition of survival signal transduction pathways. 2001 May 1 1
37 11751518 Genistein elicits pleiotropic molecular effects on head and neck cancer cells. 2001 Dec 1
38 11074606 Low-dose genistein induces cyclin-dependent kinase inhibitors and G(1) cell-cycle arrest in human prostate cancer cells. 2000 Oct 1
39 10340389 Induction of apoptosis in breast cancer cells MDA-MB-231 by genistein. 1999 May 20 1