Staurosporine

BCL2 associated X, apoptosis regulator ; Homo sapiens







49 Article(s)
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1 34022923 The effects of a mitochondrial targeted peptide (elamipretide/SS31) on BAX recruitment and activation during apoptosis. 2021 May 22 1
2 30686270 Staurosporine induces apoptosis in pancreatic carcinoma cells PaTu 8988t and Panc-1 via the intrinsic signaling pathway. 2019 Jan 28 1
3 30690742 Automated E-FRET microscope for dynamical live-cell FRET imaging. 2019 Apr 6
4 25627690 Paraoxonase 2 serves a proapopotic function in mouse and human cells in response to the Pseudomonas aeruginosa quorum-sensing molecule N-(3-Oxododecanoyl)-homoserine lactone. 2015 Mar 13 1
5 26356820 Bax-PGAM5L-Drp1 complex is required for intrinsic apoptosis execution. 2015 Oct 6 3
6 24963283 Calbindin-D28K Prevents Staurosporin-induced Bax Cleavage and Membrane Permeabilization. 2014 Jun 1
7 23333591 Involvement of PI 3 kinase/Akt-dependent Bad phosphorylation in Toxoplasma gondii-mediated inhibition of host cell apoptosis. 2013 Apr 1
8 22484496 Mitofusin 1 inhibits an apoptosis-associated amino-terminal conformational change in Bax, but not its mitochondrial translocation, in a GTPase-dependent manner. 2012 Oct 1 1
9 21915333 Modulation of cellular Hsp72 levels in undifferentiated and neuron-like SH-SY5Y cells determines resistance to staurosporine-induced apoptosis. 2011 1
10 20333643 LPLI inhibits apoptosis upstream of Bax translocation via a GSK-3beta-inactivation mechanism. 2010 Jul 3
11 18983973 E-cadherin decreased human breast cancer cells sensitivity to staurosporine by up-regulating Bcl-2 expression. 2009 Jan 1 1
12 19211028 Beta-hydroxy-beta-methylbutyrate (HMB) stimulates myogenic cell proliferation, differentiation and survival via the MAPK/ERK and PI3K/Akt pathways. 2009 May 1
13 19261878 Histone deacetylase inhibitors prevent p53-dependent and p53-independent Bax-mediated neuronal apoptosis through two distinct mechanisms. 2009 Mar 4 1
14 19657228 The C-terminus of interferon gamma receptor beta chain (IFNgammaR2) has antiapoptotic activity as a Bax inhibitor. 2009 Sep 1
15 19767770 A novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathways. 2009 Dec 17 1
16 17724464 Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist. 2008 Feb 28 1
17 18664199 [Effect of staurosporine induced apoptosis of MCF7/GFP-Bax stable cell line on Bax translocation from cytosol into mitochondria]. 2008 Apr 7
18 17340627 Mitochondrial-targeted active Akt protects SH-SY5Y neuroblastoma cells from staurosporine-induced apoptotic cell death. 2007 Sep 1 1
19 16239929 Smac/DIABLO is not released from mitochondria during apoptotic signalling in cells deficient in cytochrome c. 2006 Jul 1
20 16709574 JNK- and p38 kinase-mediated phosphorylation of Bax leads to its activation and mitochondrial translocation and to apoptosis of human hepatoma HepG2 cells. 2006 Jul 28 4
21 16857185 Hsp105 family proteins suppress staurosporine-induced apoptosis by inhibiting the translocation of Bax to mitochondria in HeLa cells. 2006 Oct 15 1
22 15772159 Oligomeric Bax is a component of the putative cytochrome c release channel MAC, mitochondrial apoptosis-induced channel. 2005 May 3
23 15878861 Activated mitofusin 2 signals mitochondrial fusion, interferes with Bax activation, and reduces susceptibility to radical induced depolarization. 2005 Jul 1 2
24 16061221 Distinct domains of Bcl-XL are involved in Bax and Bad antagonism and in apoptosis inhibition. 2005 Oct 1 1
25 16303606 Effect of progesterone on the expression of bax and bcl-2 and on caspase activity in bovine luteal cells. 2005 Dec 1
26 14752512 Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis. 2004 May 2
27 14985459 Staurosporine induces apoptosis of melanoma by both caspase-dependent and -independent apoptotic pathways. 2004 Feb 1
28 15102863 BOK and NOXA are essential mediators of p53-dependent apoptosis. 2004 Jul 2 1
29 15336502 Human alphaA- and alphaB-crystallins prevent UVA-induced apoptosis through regulation of PKCalpha, RAF/MEK/ERK and AKT signaling pathways. 2004 Sep 2
30 15669141 Human alphaA- and alphaB-crystallins prevent UVA-induced apoptosis through regulation of PKCalpha, RAF/MEK/ERK and AKT signaling pathways. 2004 Dec 2
31 12652309 Cytoprotective membrane-permeable peptides designed from the Bax-binding domain of Ku70. 2003 Apr 1
32 12808108 Nonredundant role of Bax and Bak in Bid-mediated apoptosis. 2003 Jul 1
33 11842081 The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria. 2002 Apr 19 4
34 11883953 Bcl-X(L) and calyculin A prevent translocation of Bax to mitochondria during apoptosis. 2002 Mar 15 1
35 11909872 Bax-mediated Ca2+ mobilization promotes cytochrome c release during apoptosis. 2002 Jun 7 2
36 12058280 Defective Bax activation in Hodgkin B-cell lines confers resistance to staurosporine-induced apoptosis. 2002 Jul 2
37 12097139 Biphasic translocation of Bax to mitochondria. 2002 Oct 1 1
38 12393866 Regulation of intracellular pH mediates Bax activation in HeLa cells treated with staurosporine or tumor necrosis factor-alpha. 2002 Dec 20 2
39 11136736 Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells. 2001 Apr 13 1
40 11296547 Non-steroidal anti-inflammatory drugs protect against chondrocyte apoptotic death. 2001 1
41 11487718 Subcellular redistribution of BAX during apoptosis induced by anticancer drugs. 2001 Aug 3
42 11513857 The protonophore CCCP induces mitochondrial permeability transition without cytochrome c release in human osteosarcoma cells. 2001 Aug 10 1
43 11526446 Bax translocation to mitochondria subsequent to a rapid loss of mitochondrial membrane potential. 2001 Sep 1
44 11568012 Interleukin-5 inhibits translocation of Bax to the mitochondria, cytochrome c release, and activation of caspases in human eosinophils. 2001 Oct 1 1
45 10713725 Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells. 2000 Jan 2
46 11029754 N-terminal cleavage of bax by calpain generates a potent proapoptotic 18-kDa fragment that promotes bcl-2-independent cytochrome C release and apoptotic cell death. 2000 Sep 18 1
47 10217266 Endogenous bax translocation in SH-SY5Y human neuroblastoma cells and cerebellar granule neurons undergoing apoptosis. 1999 May 3
48 10509013 A selection system for human apoptosis inhibitors using yeast. 1999 Sep 30 1
49 9108035 Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis. 1997 Apr 15 1