Title : Mitofusin 1 inhibits an apoptosis-associated amino-terminal conformational change in Bax, but not its mitochondrial translocation, in a GTPase-dependent manner.

Pub. Date : 2012 Oct 1

PMID : 22484496






1 Functional Relationships(s)
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1 Furthermore, staurosporine-induced amino-terminal activation of Bax was significantly delayed in Mfn1-shRNA transfected (Mfn1-depleted) HeLa cells compared to cells transfected with control shRNA. Staurosporine BCL2 associated X, apoptosis regulator Homo sapiens