Title : Paraoxonase 2 serves a proapopotic function in mouse and human cells in response to the Pseudomonas aeruginosa quorum-sensing molecule N-(3-Oxododecanoyl)-homoserine lactone.

Pub. Date : 2015 Mar 13

PMID : 25627690






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Coupled with previous data, these results also indicate that PON2 uses its lactonase activity to prevent Bax- and Bak-dependent apoptosis in response to common proapoptotic drugs like doxorubicin and staurosporine, but activates Bax- and Bak-independent apoptosis in response to C12. Staurosporine BCL2 associated X, apoptosis regulator Homo sapiens