Title : In vitro and in vivo anticancer effects of marmesin in U937 human leukemia cells are mediated via mitochondrial-mediated apoptosis, cell cycle arrest, and inhibition of cancer cell migration.

Pub. Date : 2018 Feb

PMID : 29251335






1 Functional Relationships(s)
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1 It was observed that marmesin treatment triggered upregulation of Bax and downregulation of Bcl-2 causing significant increase in the Bax/Bcl-2 ratio, marmesin could also induce ROS mediated alterations in mitochondrial membrane potential. ros BCL2 associated X, apoptosis regulator Homo sapiens