Histidine

renin ; Homo sapiens







40 Article(s)
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1 20977208 Mass spectrometric characterization of modifications to angiotensin II by lipid peroxidation products, 4-oxo-2(E)-nonenal and 4-hydroxy-2(E)-nonenal. 2010 Nov 15 1
2 17261087 The His-Pro-Phe motif of angiotensinogen is a crucial determinant of the substrate specificity of renin. 2007 Feb 8
3 16872275 Polymerization of human angiotensinogen: insights into its structural mechanism and functional significance. 2006 Nov 15 1
4 15942685 Roles of His9 (P2 subsite) and His13 (P3' subsite) in angiotensinogen for catalytic reaction of renin. 2005 Jul 1
5 9273895 New renin inhibitors containing novel analogues of statine. 1997 Aug 3
6 9352462 Potent in vivo inhibitors of rat renin: analogues of human and rat angiotensinogen sequences containing different classes of pseudodipeptides at the scissile site. 1997 Oct 2
7 9388263 Critical role of asparagine 1065 of human alpha2-macroglobulin in formation and reactivity of the thiol ester. 1997 Dec 5 1
8 7493993 Crystallographic studies on the binding modes of P2-P3 butanediamide renin inhibitors. 1995 Dec 8 1
9 7663352 Crystal structure of human pepsin and its complex with pepstatin. 1995 May 1
10 8107115 X-ray analysis at 2.0 A resolution of mouse submaxillary renin complexed with a decapeptide inhibitor CH-66, based on the 4-16 fragment of rat angiotensinogen. 1994 Feb 11 1
11 7678159 Renin inhibitors as an example of presumptive irrelevant positive findings in the Salmonella/mammalian microsome assay (Ames test). 1993 Feb 2
12 8512070 A continuous fluorescence assay of renin activity. 1993 May 1 2
13 1443599 An ultrasensitive human immunodeficiency virus type 1 protease radioimmuno rate assay with a potential for monitoring blood levels of protease inhibitors in acquired immunodeficiency disease syndrome patients. 1992 Nov 1 1
14 1524216 Intramolecularly quenched fluorogenic peptide substrates for human renin. 1992 May 15 3
15 1716913 Metal affinity chromatography of recombinant HIV-1 reverse transcriptase containing a human renin cleavable metal binding domain. 1991 Aug 1
16 1797705 Synthesis of human angiotensinogen (1-17) containing one of the putative glycosylation binding sites and its hydrolysis by human renin and porcine pepsin. 1991 Oct 3
17 1799412 Characterization of recombinant human renin: kinetics, pH-stability, and peptidomimetic inhibitor binding. 1991 Oct 1
18 1812733 Substrate analogue renin inhibitors containing replacements of histidine in P2 or isosteres of the amide bond between P3 and P2 sites. 1991 1
19 2100004 Solvent induced conformational changes in renin inhibitor polypeptide. 1990 1
20 2184838 Substrate specificity and inhibitor structure-activity relationships of recombinant human renin: implications in the in vivo evaluation of renin inhibitors. 1990 Apr 1
21 2186807 Substrate specificity of recombinant human renal renin: effect of histidine in the P2 subsite on pH dependence. 1990 Mar 27 7
22 2266553 X-ray analyses of aspartic proteinases. III Three-dimensional structure of endothiapepsin complexed with a transition-state isostere inhibitor of renin at 1.6 A resolution. 1990 Dec 20 2
23 2520246 Characterization of impurities in a synthetic renin substrate peptide by fast-atom bombardment mass spectrometry and hybrid tandem mass spectrometry. 1989 Sep 2
24 3126296 Inhibition of porcine pepsin by two substrate analogues containing statine. The effect of histidine at the P2 subsite on the inhibition of aspartic proteinases. 1988 Mar 2
25 3275777 Design, structure-activity, and molecular modeling studies of potent renin inhibitory peptides having N-terminal Nin-For-Trp (Ftr): angiotensinogen congeners modified by P1-P1' Phe-Phe, Sta, Leu psi[CH(OH)CH2]Val or leu psi[CH2NH]Val substitutions. 1988 Jan 1
26 2485065 Crystallographic studies of reduced bond inhibitors complexed with an aspartic proteinase. 1987 3
27 3305946 New inhibitors of human renin that contain novel Leu-Val replacements. 1987 Sep 1
28 3543358 Pepstatin analogues as novel renin inhibitors. 1986 Jul 1
29 3003303 Will renin inhibitors influence decision-making in antihypertensive therapy? 1985 Nov 2
30 3887901 Defining the physiologic and pathophysiologic roles of renin: the role of specific inhibitors. 1985 Apr 2
31 6099385 The first Sir George Pickering memorial lecture. Which inhibitors will give us true insight into what renin really does? 1984 Jun 2
32 6380499 Conformational aspects of angiotensinogen analogues with renin inhibitory activity. 1984 Jul 31 2
33 6385771 Renin cleavage of a human kidney renin substrate analogous to human angiotensinogen, H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Ser-OH, that is human renin specific and is resistant to cathepsin D. 1984 Aug 1 12
34 6196232 Peptide inhibitors of renin in cardiovascular studies. 1983 Dec 2
35 6357563 Inhibitors of renin: present and future. 1983 2
36 6418650 Is renin a factor in the etiology of essential hypertension? 1983 Nov-Dec 2
37 19034 Conformations of synthetic tetradecapeptide renin substrate and of angiotensin I in aqueous solution. 1977 Jun 14 3
38 1009126 On the specificity of human renin. Studies with peptide inhibitors. 1976 Dec 8 1
39 5662012 Kinetics of the reaction of renin with nine synthetic peptide substrates. 1968 Jul 1 4
40 13463253 The preparation, purification, and amino acid sequence of a polypeptide renin substrate. 1957 Sep 1 2