| 1 |
34559922 | Mitogen-activated protein kinase-activated protein kinase-2 (MK2) and its role in cell survival, inflammatory signaling, and migration in promoting cancer. | 2022 Feb |
2 |
| 2 |
32647362 | Phosphorylation of steroid receptor coactivator-3 (SRC-3) at serine 857 is regulated by the p38MAPK-MK2 axis and affects NF-κB-mediated transcription. | 2020 Jul 9 |
1 |
| 3 |
31537377 | Gp130 degradation induced by epirubicin contributes to chemotherapy efficacy. | 2019 Nov 12 |
1 |
| 4 |
29128684 | MAPK p38 regulates inflammatory gene expression via tristetraprolin: Doing good by stealth. | 2018 Jan |
2 |
| 5 |
29523821 | p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage. | 2018 Mar 9 |
1 |
| 6 |
27280388 | Phosphorylation of the RNA-binding protein Dazl by MAPKAP kinase 2 regulates spermatogenesis. | 2016 Aug 1 |
1 |
| 7 |
27492266 | Stress-dependent phosphorylation of myocardin-related transcription factor A (MRTF-A) by the p38(MAPK)/MK2 axis. | 2016 Aug 5 |
7 |
| 8 |
25693418 | The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation. | 2015 Feb 18 |
2 |
| 9 |
23220022 | Phosphorylation of epidermal growth factor receptor at serine 1047 by MAP kinase-activated protein kinase-2 in cultured lung epithelial cells treated with flagellin. | 2013 Jan 15 |
1 |
| 10 |
23482664 | Signaling by p38 MAPK stimulates nuclear localization of the microprocessor component p68 for processing of selected primary microRNAs. | 2013 Mar 12 |
2 |
| 11 |
24020373 | Endoplasmic reticulum-associated ubiquitin-conjugating enzyme Ube2j1 is a novel substrate of MK2 (MAPKAP kinase-2) involved in MK2-mediated TNFα production. | 2013 Dec 1 |
2 |
| 12 |
22802261 | The p38 MAPK-MK2 axis regulates E2F1 and FOXM1 expression after epirubicin treatment. | 2012 Sep |
1 |
| 13 |
20200229 | Cross-regulation of cytokine signalling: pro-inflammatory cytokines restrict IL-6 signalling through receptor internalisation and degradation. | 2010 Mar 15 |
1 |
| 14 |
20595389 | MAPKAP kinase 2 blocks tristetraprolin-directed mRNA decay by inhibiting CAF1 deadenylase recruitment. | 2010 Sep 3 |
2 |
| 15 |
20724476 | p38 MAP kinase and MAPKAP kinases MK2/3 cooperatively phosphorylate epithelial keratins. | 2010 Oct 22 |
6 |
| 16 |
18978352 | Phosphorylation of serine 271 on 5-lipoxygenase and its role in nuclear export. | 2009 Jan 2 |
1 |
| 17 |
18021073 | Roles for TAB1 in regulating the IL-1-dependent phosphorylation of the TAB3 regulatory subunit and activity of the TAK1 complex. | 2008 Feb 1 |
1 |
| 18 |
18476811 | Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies. | 2008 Aug 1 |
2 |
| 19 |
18759402 | Recognition-domain focused chemosensors: versatile and efficient reporters of protein kinase activity. | 2008 Sep 24 |
1 |
| 20 |
17237275 | Cell cycle phenotype-based optimization of G2-abrogating peptides yields CBP501 with a unique mechanism of action at the G2 checkpoint. | 2007 Jan |
1 |
| 21 |
17510053 | Hsp27 regulates Akt activation and polymorphonuclear leukocyte apoptosis by scaffolding MK2 to Akt signal complex. | 2007 Jul 27 |
5 |
| 22 |
16278218 | Phosphorylation of HSF1 by MAPK-activated protein kinase 2 on serine 121, inhibits transcriptional activity and promotes HSP90 binding. | 2006 Jan 13 |
3 |
| 23 |
16456544 | MAPKAPK-2-mediated LIM-kinase activation is critical for VEGF-induced actin remodeling and cell migration. | 2006 Feb 22 |
1 |
| 24 |
16508015 | Posttranslational regulation of tristetraprolin subcellular localization and protein stability by p38 mitogen-activated protein kinase and extracellular signal-regulated kinase pathways. | 2006 Mar |
1 |
| 25 |
15850461 | The phosphorylation of CapZ-interacting protein (CapZIP) by stress-activated protein kinases triggers its dissociation from CapZ. | 2005 Jul 1 |
5 |
| 26 |
15014438 | MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay. | 2004 Mar 24 |
2 |
| 27 |
15084475 | Role of p38 MAPK and MAPKAPK-2 in angiotensin II-induced Akt activation in vascular smooth muscle cells. | 2004 Aug |
1 |
| 28 |
15271996 | Proteomic identification of Bcl2-associated athanogene 2 as a novel MAPK-activated protein kinase 2 substrate. | 2004 Oct 1 |
2 |
| 29 |
12582162 | The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3. | 2003 Apr 18 |
3 |
| 30 |
12761892 | Retaining of the assembly capability of vimentin phosphorylated by mitogen-activated protein kinase-activated protein kinase-2. | 2003 Jun 1 |
4 |
| 31 |
12861023 | Proteomic identification of 14-3-3zeta as a mitogen-activated protein kinase-activated protein kinase 2 substrate: role in dimer formation and ligand binding. | 2003 Aug |
1 |
| 32 |
11844797 | Arachidonic acid promotes phosphorylation of 5-lipoxygenase at Ser-271 by MAPK-activated protein kinase 2 (MK2). | 2002 Apr 26 |
3 |
| 33 |
11896587 | Role of MAP kinases in UVB-induced phosphorylation of p53 at serine 20. | 2002 Feb 28 |
1 |
| 34 |
12171600 | Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways. | 2002 Oct 15 |
2 |
| 35 |
11551945 | Cell type-specific inhibition of the ETS transcription factor ER81 by mitogen-activated protein kinase-activated protein kinase 2. | 2001 Nov 9 |
2 |
| 36 |
10383393 | Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor alpha by phosphorylation. | 1999 Jul 2 |
1 |
| 37 |
9528766 | Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation. | 1998 Apr |
2 |
| 38 |
9774459 | Phosphorylation of alphaB-crystallin in mitotic cells and identification of enzymatic activities responsible for phosphorylation. | 1998 Oct 23 |
9 |
| 39 |
8774846 | A comparison of the substrate specificity of MAPKAP kinase-2 and MAPKAP kinase-3 and their activation by cytokines and cellular stress. | 1996 Sep 2 |
1 |
| 40 |
8142647 | Interleukin-3 and granulocyte-macrophage colony-stimulating factor induce activation of the MAPKAP kinase 2 resulting in in vitro serine phosphorylation of the small heat shock protein (Hsp 27). | 1994 Apr 1 |
3 |
| 41 |
8280084 | The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2. | 1993 Dec 15 |
1 |