Title : Signaling by p38 MAPK stimulates nuclear localization of the microprocessor component p68 for processing of selected primary microRNAs.

Pub. Date : 2013 Mar 12

PMID : 23482664






2 Functional Relationships(s)
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1 Through yeast two-hybrid screening, we identified p68 (also known as DDX5), a key component of the Drosha complex that processes pri-miRNAs, as an MK2-interacting protein, and we found that MK2 phosphorylated p68 at Ser(197) in cells. Serine MAPK activated protein kinase 2 Homo sapiens
2 Nuclear localization of p68 depended on MK2-mediated phosphorylation of Ser(197). Serine MAPK activated protein kinase 2 Homo sapiens