Title : MAPKAP kinase 2 blocks tristetraprolin-directed mRNA decay by inhibiting CAF1 deadenylase recruitment.

Pub. Date : 2010 Sep 3

PMID : 20595389






2 Functional Relationships(s)
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1 We find that phosphorylation of Ser-52 and Ser-178 of TTP by MK2 results in inhibition of TTP-directed deadenylation of ARE-containing RNA. Serine MAPK activated protein kinase 2 Homo sapiens
2 We find that phosphorylation of Ser-52 and Ser-178 of TTP by MK2 results in inhibition of TTP-directed deadenylation of ARE-containing RNA. Serine MAPK activated protein kinase 2 Homo sapiens