Phenylalanine

phenylalanine hydroxylase ; Rattus norvegicus







51 Article(s)
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1 26823465 Identification of the Allosteric Site for Phenylalanine in Rat Phenylalanine Hydroxylase. 2016 Apr 1 3
2 20951114 Direct evidence for a phenylalanine site in the regulatory domain of phenylalanine hydroxylase. 2011 Jan 15 2
3 20307070 Regulation of phenylalanine hydroxylase: conformational changes upon phenylalanine binding detected by hydrogen/deuterium exchange and mass spectrometry. 2010 Apr 20 1
4 16139311 L-[1-13C] phenylalanine breath test results reflect the activity of phenylalanine hydroxylase in carbon tetrachloride acute injured rat liver. 2006 Jan 18 1
5 16429477 Results of L-[1-13C]phenylalanine breath test with air isotope ratio mass spectrometry can reflect the activity of phenylalanine hydroxylase in cirrhotic rat liver. 2006 1
6 16953590 Insights into the catalytic mechanisms of phenylalanine and tryptophan hydroxylase from kinetic isotope effects on aromatic hydroxylation. 2006 Sep 12 2
7 15764292 Phenylacetylglycine, a putative biomarker of phospholipidosis: its origins and relevance to phospholipid accumulation using amiodarone treated rats as a model. 2004 May-Jun 1
8 12668065 Simultaneous measurement of phenylalanine and tyrosine in phenylketonuric plasma and dried blood by high-performance liquid chromatography. 2003 May 5 1
9 11410294 Conjugation of phenylalanine hydroxylase with polyubiquitin chains catalysed by rat liver enzymes. 2001 Jun 11 1
10 10197570 Effects of dietary mixtures of amino acids on fetal growth and maternal and fetal amino acid pools in experimental maternal phenylketonuria. 1999 Apr 1
11 9542220 [An experimental study on the effects of maternal hyperphenylalaninemia on the central nervous system and behavior of offspring rats]. 1998 Jan 1
12 9012811 The role of phenylalanine in structure-function relationships of phenylalanine hydroxylase revealed by radiation target analysis. 1997 Jan 21 1
13 8925406 Differential effects of streptozotocin-induced diabetes on phenylalanine hydroxylase protein and mRNA abundance in isolated rat liver cells. 1996 Jul 1
14 7846072 Coordinate regulation of tetrahydrobiopterin turnover and phenylalanine hydroxylase activity in rat liver cells. 1995 Jan 31 6
15 7904815 Electrostatic activation of rat phenylalanine hydroxylase. 1994 Jan 14 1
16 7929136 Regulation of rat liver phenylalanine hydroxylase. II. Substrate binding and the role of activation in the control of enzymatic activity. 1994 Oct 7 2
17 7929137 Regulation of rat liver phenylalanine hydroxylase. III. Control of catalysis by (6R)-tetrahydrobiopterin and phenylalanine. 1994 Oct 7 2
18 8323303 Products of the tyrosine-dependent oxidation of tetrahydrobiopterin by rat liver phenylalanine hydroxylase. 1993 Jul 1
19 1316838 Phenylalanine positively modulates the cAMP-dependent phosphorylation and negatively modulates the vasopressin-induced and okadaic-acid-induced phosphorylation of phenylalanine 4-monooxygenase in intact rat hepatocytes. 1992 May 15 1
20 1350256 Distribution of 4a-hydroxytetrahydropterin dehydratase in rat tissues. Comparison with the aromatic amino acid hydroxylases. 1992 May 4 1
21 1422220 Purification and biochemical characterization of recombinant rat liver phenylalanine hydroxylase produced in Escherichia coli. 1992 Apr 1
22 1730677 Phenylalanine-induced phosphorylation and activation of rat hepatic phenylalanine hydroxylase in vivo. 1992 Jan 15 4
23 2065060 Affinity labeling of the active site and the reactive sulfhydryl associated with activation of rat liver phenylalanine hydroxylase. 1991 Jul 9 1
24 2365689 Mechanism of phenylalanine regulation of phenylalanine hydroxylase. 1990 Jul 15 3
25 2722790 Evidence for the formation of the 4a-carbinolamine during the tyrosine-dependent oxidation of tetrahydrobiopterin by rat liver phenylalanine hydroxylase. 1989 May 25 1
26 2930457 Interaction with a monoclonal antibody alters the expression of co-operativity by phenylalanine hydroxylase from rat liver. 1989 Jan 15 1
27 3129035 [Detection and characteristics of membrane form of phenylalanine hydroxylase (EC 1.14.16.1) from the rat liver]. 1988 Jan 1
28 3335542 Effect of alkaline pH on the activity of rat liver phenylalanine hydroxylase. 1988 Jan 25 3
29 3356704 Reaction of rat liver phenylalanine hydroxylase with fatty acid hydroperoxides. Characterization and mechanism. 1988 Apr 25 6
30 3408719 L-[2,5-H2]phenylalanine, an alternate substrate for rat liver phenylalanine hydroxylase. 1988 May 17 5
31 2872885 Quantification of the importance of individual steps in the control of aromatic amino acid metabolism. 1986 Mar 15 1
32 3722178 Purification and state of activation of rat kidney phenylalanine hydroxylase. 1986 Jul 5 1
33 4016080 Phenylalanine hydroxylase: absolute configuration and source of oxygen of the 4a-hydroxytetrahydropterin species. 1985 Jun 4 1
34 6186515 Effects of maternal hyperphenylalaninemia on fetal brain development: a biochemical study. 1983 Mar 4
35 6681776 Effects of maternal hyperphenylalaninemia on fetal brain development: a morphological study. 1983 Mar 1
36 6838560 Ligand effects on the limited proteolysis of phenylalanine hydroxylase: evidence for multiple conformational states. 1983 Feb 10 2
37 6981644 Regulation of phenylalanine hydroxylase activity by phenylalanine in vivo, in vitro, and in perfused rat liver. 1982 Oct 10 1
38 6257849 Chronic hyperphenylalaninemia produces cerebral hyperglycinemia in immature rats. 1981 Jan 2
39 7240248 Rat liver phenylalanine hydroxylase. Activation by sulfhydryl modification. 1981 Jul 10 2
40 6446685 Phenylketonuria: clinical and experimental considerations revealed by the use of animal models. 1980 May 1
41 7430114 Relationship between the substrate activation site and catalytic site of phenylalanine hydroxylase. 1980 Nov 10 1
42 23386 Phenylalanine hydroxylase in melanoma cells. 1978 Mar 1
43 728481 Phenylalanine analogues as inhibitors of phenylalanine-hydroxylase from rat liver. New conclusions concerning kinetic behaviors of the enzyme. 1978 2
44 145879 A new experimental model of hyperphenylalaninemia in rat. Effect of p-chlorophenylalanine and cotrimoxazole. 1977 1
45 133671 The regulation of phenylalanine hydroxylase in rat tissues in vivo. Substrate- and cortisol-induced elevations in phenylalanine hydroxylase activity. 1976 Mar 15 1
46 124733 Studies on the phenylalanine hydroxylase system in vivo. An in vivo assay based on the liberation of deuterium or tritium into the body water from ring-labeled L-phenylalanine. 1975 Jun 25 1
47 4854919 The isolation and properties of phenylalanine hydroxylase from human liver. 1974 Jun 1
48 4260277 Enduring behavioral changes in rats with experimental phenylketonuria. 1972 Apr 1
49 4265522 Liver phenylalanine hydroxylase activity in relation to blood concentrations of tyrosine and phenylalanine in the rat. 1972 May 1
50 6067632 The effect of phenylalanine administration on the activities of phenylalanine hydroxylase, some aminotransferases and decarboxylases in adult rats. 1967 1