Melanins

tyrosinase ; Mus musculus







244 Article(s)
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51 30366788 Design, synthesis and anti-melanogenic effect of cinnamamide derivatives. 2018 Nov 15 3
52 30551624 Evaluation of the Novel Synthetic Tyrosinase Inhibitor (Z)-3-(3-bromo-4-hydroxybenzylidene)thiochroman-4-one (MHY1498) In Vitro and In Silico. 2018 Dec 13 2
53 28241436 Gomisin N Inhibits Melanogenesis through Regulating the PI3K/Akt and MAPK/ERK Signaling Pathways in Melanocytes. 2017 Feb 22 1
54 28381809 Coumestrol Down-Regulates Melanin Production in Melan-a Murine Melanocytes through Degradation of Tyrosinase. 2017 1
55 28456625 Effects of matsutake mushroom scent compounds on tyrosinase and murine B16-F10 melanoma cells. 2017 Jun 10 1
56 28669590 Tranexamic acid inhibits melanogenesis by activating the autophagy system in cultured melanoma cells. 2017 Oct 1
57 28726389 Antimelanogenic Effect of Urolithin A and Urolithin B, the Colonic Metabolites of Ellagic Acid, in B16 Melanoma Cells. 2017 Aug 16 1
58 29019920 Pratol, an O-Methylated Flavone, Induces Melanogenesis in B16F10 Melanoma Cells via p-p38 and p-JNK Upregulation. 2017 Oct 11 1
59 26656314 Effect of apigenin-7-glucoside, genkwanin and naringenin on tyrosinase activity and melanin synthesis in B16F10 melanoma cells. 2016 Jan 1 1
60 26748310 Chaetocin inhibits IBMX-induced melanogenesis in B16F10 mouse melanoma cells through activation of ERK. 2016 Feb 5 1
61 26750991 Ensemble-Based Virtual Screening Led to the Discovery of New Classes of Potent Tyrosinase Inhibitors. 2016 Feb 22 2
62 26901194 Hinokitiol Inhibits Melanogenesis via AKT/mTOR Signaling in B16F10 Mouse Melanoma Cells. 2016 Feb 18 1
63 27084445 Inhibitory effect of Cinnamomum osmophloeum Kanehira ethanol extracts on melanin synthesis via repression of tyrosinase expression. 2016 Sep 3
64 27224051 Novel Hypomorphic Alleles of the Mouse Tyrosinase Gene Induced by CRISPR-Cas9 Nucleases Cause Non-Albino Pigmentation Phenotypes. 2016 1
65 27347933 MicroRNA-21a-5p Functions on the Regulation of Melanogenesis by Targeting Sox5 in Mouse Skin Melanocytes. 2016 Jun 24 2
66 27424198 Traditional herbal prescription LASAP-C inhibits melanin synthesis in B16F10 melanoma cells and zebrafish. 2016 Jul 16 1
67 27543340 The activation of melanogenesis by p-CREB and MITF signaling with extremely low-frequency electromagnetic fields on B16F10 melanoma. 2016 Oct 1 1
68 27623800 Anti-wrinkle and anti-whitening effects of jucá (Libidibia ferrea Mart.) extracts. 2016 Nov 1
69 27655047 Extracts of Morus nigra L. Leaves Standardized in Chlorogenic Acid, Rutin and Isoquercitrin: Tyrosinase Inhibition and Cytotoxicity. 2016 1
70 27980392 Increased therapeutic efficacy of a newly synthesized tyrosinase inhibitor by solid lipid nanoparticles in the topical treatment of hyperpigmentation. 2016 1
71 27983977 Inhibition of tyrosinase activity and melanin production by the chalcone derivative 1-(2-cyclohexylmethoxy-6-hydroxy-phenyl)-3-(4-hydroxymethyl-phenyl)-propenone. 2016 Nov 25 1
72 25584612 Hair dyes resorcinol and lawsone reduce production of melanin in melanoma cells by tyrosinase activity inhibition and decreasing tyrosinase and microphthalmia-associated transcription factor (MITF) expression. 2015 Jan 9 1
73 25661350 Compounds isolated from the aerial part of Crataegus azarolus inhibit growth of B16F10 melanoma cells and exert a potent inhibition of the melanin synthesis. 2015 Feb 1
74 25690686 The antimycotic agent clotrimazole inhibits melanogenesis by accelerating ERK and PI3K-/Akt-mediated tyrosinase degradation. 2015 May 1
75 25716948 Berberine regulates melanin synthesis by activating PI3K/AKT, ERK and GSK3β in B16F10 melanoma cells. 2015 Apr 1
76 25726329 Effect of the tyrosinase inhibitor (S)-N-trans-feruloyloctopamine from garlic skin on tyrosinase gene expression and melanine accumulation in melanoma cells. 2015 Apr 1 2
77 25744361 Development of radioiodine-labeled 4-hydroxyphenylcysteamine for specific diagnosis of malignant melanoma. 2015 Jun 2
78 25869056 Andrographolide suppresses melanin synthesis through Akt/GSK3β/β-catenin signal pathway. 2015 Jul 2
79 25934572 Baicalin-induced Akt activation decreases melanogenesis through downregulation of microphthalmia-associated transcription factor and tyrosinase. 2015 Aug 15 1
80 25943301 The natural yeast extract isolated by ethanol precipitation inhibits melanin synthesis by modulating tyrosinase activity and downregulating melanosome transfer. 2015 1
81 25975099 Methyl gallate from Acer barbinerve decreases melanin synthesis in Mel-Ab cells. 2015 Jan 1
82 26235587 (Z)-2-(Benzo[d]thiazol-2-ylamino)-5-(substituted benzylidene)thiazol-4(5H)-one Derivatives as Novel Tyrosinase Inhibitors. 2015 1
83 26389869 Anti-Oxidant, Anti-Aging, and Anti-Melanogenic Properties of the Essential Oils from Two Varieties of Alpinia zerumbet. 2015 Sep 14 1
84 26500815 Antityrosinase activity of Euphorbia characias extracts. 2015 1
85 26544630 Analogues of ethionamide, a drug used for multidrug-resistant tuberculosis, exhibit potent inhibition of tyrosinase. 2015 Dec 1 2
86 26601420 The DNA methylation inhibitor 5-azacytidine decreases melanin synthesis by inhibiting CREB phosphorylation. 2015 Oct 1
87 26633377 Repositioning of Thiourea-Containing Drugs as Tyrosinase Inhibitors. 2015 Dec 2 1
88 24212072 Eupafolin, a skin whitening flavonoid isolated from Phyla nodiflora, downregulated melanogenesis: Role of MAPK and Akt pathways. 2014 1
89 24445257 Hispolon decreases melanin production and induces apoptosis in melanoma cells through the downregulation of tyrosinase and microphthalmia-associated transcription factor (MITF) expressions and the activation of caspase-3, -8 and -9. 2014 Jan 17 1
90 24632067 Betulinic acid isolated from Vitis amurensis root inhibits 3-isobutyl-1-methylxanthine induced melanogenesis via the regulation of MEK/ERK and PI3K/Akt pathways in B16F10 cells. 2014 Jun 1
91 24984260 Somatic mosaicism and allele complexity induced by CRISPR/Cas9 RNA injections in mouse zygotes. 2014 Sep 1 1
92 25126713 Inhibitory effects of p-alkylaminophenol on melanogenesis. 2014 Sep 1 2
93 25244016 Inhibitory effects of adlay extract on melanin production and cellular oxygen stress in B16F10 melanoma cells. 2014 Sep 19 1
94 25898764 The mixture of different parts of Nelumbo nucifera and two bioactive components inhibited tyrosinase activity and melanogenesis. 2014 Nov-Dec 1
95 26579376 Inhibition of tyrosinase activity and melanine pigmentation by 2-hydroxytyrosol. 2014 Apr 1
96 23621022 Melanogenesis of methyl myristate loaded niosomes in B16F10 melanoma cells. 2013 Apr 1
97 23776585 Transplantation of melanocytes obtained from the skin ameliorates apomorphine-induced abnormal behavior in rodent hemi-parkinsonian models. 2013 1
98 23781272 Inhibitory Effect of Arctigenin from Fructus Arctii Extract on Melanin Synthesis via Repression of Tyrosinase Expression. 2013 1
99 23876066 Caffeic acid phenethyl ester inhibits alpha-melanocyte stimulating hormone-induced melanin synthesis through suppressing transactivation activity of microphthalmia-associated transcription factor. 2013 Aug 23 2
100 23995664 Okadaic acid suppresses melanogenesis via proteasomal degradation of tyrosinase. 2013 1