Chlormethiazole

cytochrome P450 family 2 subfamily E member 1 ; Homo sapiens







16 Article(s)
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Title
Pub. Year
#Total Relationships
1 33972357 Clomethiazole inhibits cytochrome P450 2E1 and improves alcoholic liver disease. 2022 Apr 1
2 30641601 [The role of Cytochrom P4502E1 in Alcoholic Liver Disease and alcohol mediated carcinogenesis]. 2019 Jan 2
3 28987868 Impairment of Akt activity by CYP2E1 mediated oxidative stress is involved in chronic ethanol-induced fatty liver. 2018 Apr 2
4 30362092 Chronic Ethanol Consumption and Generation of Etheno-DNA Adducts in Cancer-Prone Tissues. 2018 1
5 28336091 Altered cellular metabolism of HepG2 cells caused by microcystin-LR. 2017 Jun 1
6 29404485 Increased ethanol-inducible cytochrome P450-2E1 and cytochrome P450 isoforms in exosomes of alcohol-exposed rodents and patients with alcoholism through oxidative and endoplasmic reticulum stress. 2017 Sep 2
7 26739624 A cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: Application to acetaminophen. 2016 Feb 1 1
8 27149898 Selective Time- and NADPH-Dependent Inhibition of Human CYP2E1 by Clomethiazole. 2016 Aug 1
9 25427901 Alcohol and cancer: an overview with special emphasis on the role of acetaldehyde and cytochrome P450 2E1. 2015 2
10 23400919 The role of cytochrome P450 2E1 in ethanol-mediated carcinogenesis. 2013 2
11 16963249 Docosahexaenoic acid induces apoptosis in CYP2E1-containing HepG2 cells by activating the c-Jun N-terminal protein kinase related mitochondrial damage. 2007 May 4
12 17963120 Involvement of reactive oxygen species in Microcystin-LR-induced cytogenotoxicity. 2007 Dec 1
13 11133247 Inhibition of CYP2E1 with natural agents may be a feasible strategy for minimizing the hepatotoxicity of ethanol. 2001 Jan 1
14 10461422 Protective effect of chlormethiazole, a sedative, against acetaminophen-induced liver injury in mice. 1999 Jul 1
15 9695719 Inhibition of CYP2E1 by chlormethiazole as measured by chlorzoxazone pharmacokinetics in patients with alcoholism and in healthy volunteers. 1998 Jul 6
16 9328319 Chlormethiazole inhibition of cytochrome P450 2E1 as assessed by chlorzoxazone hydroxylation in humans. 1997 Oct 5