Superoxides

MAPK associated protein 1 ; Homo sapiens







62 Article(s)
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1 25476852 Posttranslational modification of Sirt6 activity by peroxynitrite. 2015 Feb 1
2 24375019 The reduction of EPSC amplitude in CA1 pyramidal neurons by the peroxynitrite donor SIN-1 requires Ca2+ influx via postsynaptic non-L-type voltage gated calcium channels. 2014 Feb 1
3 24405159 Reversal of SIN-1-induced eNOS dysfunction by the spin trap, DMPO, in bovine aortic endothelial cells via eNOS phosphorylation. 2014 May 2
4 21030671 Differential effects of peroxynitrite on contractile protein properties in fast- and slow-twitch skeletal muscle fibers of rat. 2011 Mar 1
5 21497204 Cytotoxicity and genotoxicity studies of two free-radical generators (AAPH and SIN-1) in human microvascular endothelial cells (HMEC-1) and human peripheral lymphocytes. 2011 May 18 1
6 21981804 Superoxide anion contributes to the induction of tumor necrosis factor alpha (TNF╬▒) through activation of the MKK3/6-p38 MAPK cascade in rat microglia. 2011 Nov 8 2
7 19895807 The role of superoxide anion in the inhibitory effect of SIN-1 in thrombin-activated human platelet adhesion. 2010 Feb 10 2
8 20099714 P38 MAP kinase in valve interstitial cells is activated by angiotensin II or nitric oxide/peroxynitrite, but reduced by Toll-like receptor-2 stimulation. 2009 Nov 1
9 18616952 Human neutrophil-pulmonary microvascular endothelial cell interactions in vitro: differential effects of nitric oxide vs. peroxynitrite. 2008 Aug 1
10 17206381 Antioxidant enzyme inhibitors enhance peroxynitrite-induced cell death in U937 cells. 2007 Jul 1
11 17977674 Peroxynitrite donor impairs excitability of hippocampal CA1 neurons by inhibiting voltage-gated potassium currents. 2007 Dec 10 1
12 16843826 Inefficient spin trapping of superoxide in the presence of nitric-oxide: implications for studies on nitric-oxide synthase uncoupling. 2006 Aug 1 1
13 14657004 Nitric oxide and reactive oxygen species exert opposing effects on the stability of hypoxia-inducible factor-1alpha (HIF-1alpha) in explants of human pial arteries. 2004 Feb 2
14 15105207 Peroxynitrite inactivates tissue plasminogen activator. 2004 May 1
15 15129734 Detection of superoxide and peroxynitrite in model systems and mitochondria by the luminol analogue L-012. 2004 Mar 1
16 15202767 Inhibition of SIN-1-induced change in mitochondrial membrane permeability in PC12 cells by dopamine. 2004 Jul 1
17 15281495 Peroxynitrite decreases hemostasis in human plasma in vitro. 2004 Jul 1
18 15289284 GEA 3162 decomposes to co-generate nitric oxide and superoxide and induces apoptosis in human neutrophils via a peroxynitrite-dependent mechanism. 2004 Sep 1
19 15302679 Nitric oxide donors inhibit 5-hydroxytryptamine (5-HT) uptake by the human 5-HT transporter (SERT). 2004 Sep 2
20 15326075 Nitroaspirins and morpholinosydnonimine but not aspirin inhibit the formation of superoxide and the expression of gp91phox induced by endotoxin and cytokines in pig pulmonary artery vascular smooth muscle cells and endothelial cells. 2004 Aug 31 1
21 15901411 Novel chemiluminescence-inducing cocktails, part I: the role in light emission of combinations of luminal with SIN-1, selenite, albumin, glucose oxidase and Co2+. 2004 1
22 14502568 Cyclic AMP and cyclic GMP independent stimulation of ventricular calcium current by peroxynitrite donors in guinea pig myocytes. 2003 Nov 1
23 14565769 Inhibition of peroxynitrite-mediated LDL oxidation by prenylated flavonoids: the alpha,beta-unsaturated keto functionality of 2'-hydroxychalcones as a novel antioxidant pharmacophore. 2003 Oct 1
24 11170241 Mechanisms of nitric oxide-induced cytotoxicity in normal human hepatocytes. 2001 1
25 11369646 In vivo and in vitro apoptosis of human thymocytes are associated with nitrotyrosine formation. 2001 Jun 1 1
26 11417851 Danchunhwan water extract prevents apoptotic death by peroxynitrite and nitric oxide in human dopaminergic neuroblastoma SH-SY5Y cells. 2001 May 1
27 11677273 SIN-1-induced cytotoxicity in mixed cortical cell culture: peroxynitrite-dependent and -independent induction of excitotoxic cell death. 2001 Oct 2
28 11962084 [Effects of nitric oxide donor SIN-1 on calcium transport in rat cardiac sarcoplasmic reticulum]. 2001 1
29 10660121 Nitric oxide-independent effects of nitric oxide donors on energy metabolism in erythrocytes. 2000 Mar 1 1
30 10816077 Programmed cell death in 2',3'-dideoxycytidine-resistant human monoblastoid U937 cells. 2000 Feb 1
31 10823274 Influence of SIN-1 on platelet Ca2+ handling in patients with suspected coronary artery disease: ex vivo and in vitro studies. 2000 May 4
32 10930123 The mechanism of nitric oxide and/or superoxide cytotoxicity in endothelial cells. 2000 Jun 1
33 9882464 The peroxynitrite generator, SIN-1, becomes a nitric oxide donor in the presence of electron acceptors. 1999 Jan 15 1
34 10229110 Contrasting roles for nitric oxide and peroxynitrite in the peroxidation of myelin lipids. 1999 Mar 1 2
35 10381591 Positive and negative inotropic effects of NO donors in atrial and ventricular fibres of the frog heart. 1999 Jul 15 1
36 10398565 Effect of antioxidants on induction time of luminol luminescence elicited by 3-morpholinosydnonimine (SIN-1). 1999 Mar-Apr 1
37 10489120 Formation of guanidinosuccinic acid, a stable nitric oxide mimic, from argininosuccinic acid and nitric oxide-derived free radicals. 1999 Jul 1
38 10491133 Interaction of heme oxygenase-2 with nitric oxide donors. Is the oxygenase an intracellular 'sink' for NO? 1999 Sep 1
39 10493821 Regulation of prostaglandin H2 synthase activity by nitrogen oxides. 1999 Sep 21 1
40 10496147 Melatonin inhibits the vasorelaxant action of peroxynitrite in human umbilical artery. 1999 Sep 1
41 10545203 Factors determining the selectivity of protein tyrosine nitration. 1999 Nov 15 1
42 10581309 Peroxynitrite is a positive inotropic agent in atrial and ventricular fibres of the frog heart. 1999 Dec 1 2
43 10627995 Enhancement by glucose of low density lipoprotein-oxidation by peroxynitrite. 1999 Nov 1
44 9452441 A new pathway of nitric oxide/cyclic GMP signaling involving S-nitrosoglutathione. 1998 Feb 6 1
45 9556559 Peroxynitrite increases the degradation of aconitase and other cellular proteins by proteasome. 1998 May 1 2
46 9582295 Hydrogen peroxide formation by reaction of peroxynitrite with HEPES and related tertiary amines. Implications for a general mechanism. 1998 May 22 1
47 9808374 Effects of superoxide and peroxynitrite on vascular tension in the human umbilical artery. 1998 Oct 1
48 21781879 Mechanisms of cell death induced by nitric oxide and peroxynitrite in Calu-1 cells. 1998 Aug 4 2
49 9048779 Inhibitory effect of several nitric oxide-generating compounds on purified Na+,K(+)-ATPase activity from porcine cerebral cortex. 1997 Mar 1
50 9144574 Sensitivity of human hepatocytes in culture to reactive nitrogen intermediates. 1997 Apr 17 3