Aspartic Acid

coagulation factor X ; Homo sapiens







13 Article(s)
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1 16454727 Metabolism-directed optimisation of antithrombotics: the prodrug principle. 2006 1
2 16042383 Functional mapping of charged residues of the 82-116 sequence in factor Xa: evidence that lysine 96 is a factor Va independent recognition site for prothrombin in the prothrombinase complex. 2005 Aug 2 2
3 12948396 Coagulation factor Va Glu-96-Asp-111: a chelator-sensitive site involved in function and subunit association. 2004 Jan 1 1
4 15219196 Role of the gamma-carboxyglutamic acid domain of activated factor X in the presence of calcium during inhibition by antithrombin-heparin. 2004 Jul 3
5 15347660 The critical role of the 185-189-loop in the factor Xa interaction with Na+ and factor Va in the prothrombinase complex. 2004 Nov 12 4
6 11925440 Mapping of the catalytic groove preferences of factor Xa reveals an inadequate selectivity for its macromolecule substrates. 2002 Jun 7 2
7 12149252 Prothrombinase assembly and S1 site occupation restore the catalytic activity of FXa impaired by mutation at the sodium-binding site. 2002 Oct 4 1
8 10995746 Directed glycosylation of human coagulation factor X at residue 333. Insight into factor Va-dependent prothrombin catalysis. 2000 Dec 8 1
9 10022353 Modelling of factor Xa-inhibitor complexes: a computational flexible docking approach. 1999 Feb 1 1
10 9538022 Structure/function analyses of recombinant variants of human factor Xa: factor Xa incorporation into prothrombinase on the thrombin-activated platelet surface is not mimicked by synthetic phospholipid vesicles. 1998 Apr 7 1
11 8939944 X-ray structure of active site-inhibited clotting factor Xa. Implications for drug design and substrate recognition. 1996 Nov 22 1
12 7649284 Proposed cation-pi mediated binding by factor Xa: a novel enzymatic mechanism for molecular recognition. 1995 Aug 14 1
13 8226983 The importance of specific gamma-carboxyglutamic acid residues in prothrombin. Evaluation by site-specific mutagenesis. 1993 Nov 15 1