Title : Coagulation factor Va Glu-96-Asp-111: a chelator-sensitive site involved in function and subunit association.

Pub. Date : 2004 Jan 1

PMID : 12948396






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 While mutation of Thr-104, Glu-108, Asp-112 or Tyr-100 resulted in only minor changes to FXa-mediated thrombin generation, the functions of E96A (81%), D111A (70%) and D102A (60%) mutants (where the single-letter amino acid code is used) were notably reduced. Aspartic Acid coagulation factor X Homo sapiens