Title : Hypoxia-inducible factor-1 mediates pancreatic β-cell dysfunction by intermittent hypoxia.

Pub. Date : 2020 Nov 1

PMID : 32936698






1 Functional Relationships(s)
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1 The elevated ROS levels were due to transcriptional up regulation of NADPH oxidase (NOX)-4 mRNA, protein and enzymatic activity and these responses were absent in HIF-1alpha HET mice as well as in beta-HIF-1-/- mice. Reactive Oxygen Species NADPH oxidase 4 Mus musculus