Metformin

amyloid beta precursor protein ; Homo sapiens







10 Article(s)
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Pub. Year
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1 35134385 Metformin in Alzheimer's disease: An overview of potential mechanisms, preclinical and clinical findings. 2022 Mar 4
2 35286856 Aβ-responsive metformin-based supramolecular synergistic nanodrugs for Alzheimer's disease via enhancing microglial Aβ clearance. 2022 Apr 4
3 35153733 Deciphering the Roles of Metformin in Alzheimer's Disease: A Snapshot. 2021 2
4 31610847 Metabolic stress is a primary pathogenic event in transgenic Caenorhabditis elegans expressing pan-neuronal human amyloid beta. 2019 Oct 15 1
5 28589443 Metformin - a Future Therapy for Neurodegenerative Diseases : Theme: Drug Discovery, Development and Delivery in Alzheimer's Disease Guest Editor: Davide Brambilla. 2017 Dec 1
6 26967226 Metformin Facilitates Amyloid-β Generation by β- and γ-Secretases via Autophagy Activation. 2016 5
7 27403417 Metformin Alleviated Aβ-Induced Apoptosis via the Suppression of JNK MAPK Signaling Pathway in Cultured Hippocampal Neurons. 2016 7
8 27554603 Metformin activation of AMPK-dependent pathways is neuroprotective in human neural stem cells against Amyloid-beta-induced mitochondrial dysfunction. 2016 Oct 1 2
9 25667085 Metformin increases APP expression and processing via oxidative stress, mitochondrial dysfunction and NF-κB activation: Use of insulin to attenuate metformin's effect. 2015 May 2
10 19237574 Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription. 2009 Mar 10 6