benzimidazole

insulin like growth factor 1 receptor ; Homo sapiens







5 Article(s)
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Pub. Year
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1 21220496 Drug efflux by breast cancer resistance protein is a mechanism of resistance to the benzimidazole insulin-like growth factor receptor/insulin receptor inhibitor, BMS-536924. 2011 Jan 1
2 20153189 SAR of PXR transactivation in benzimidazole-based IGF-1R kinase inhibitors. 2010 Mar 1 1
3 20545947 Design of potent IGF1-R inhibitors related to bis-azaindoles. 2010 Aug 1
4 18572407 Balancing oral exposure with Cyp3A4 inhibition in benzimidazole-based IGF-IR inhibitors. 2008 Jul 15 1
5 18763755 Discovery and evaluation of 4-(2-(4-chloro-1H-pyrazol-1-yl)ethylamino)-3-(6-(1-(3-fluoropropyl)piperidin-4-yl)-4-methyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (BMS-695735), an orally efficacious inhibitor of insulin-like growth factor-1 receptor kinase with broad spectrum in vivo antitumor activity. 2008 Oct 9 1