Title : Drug efflux by breast cancer resistance protein is a mechanism of resistance to the benzimidazole insulin-like growth factor receptor/insulin receptor inhibitor, BMS-536924.

Pub. Date : 2011 Jan

PMID : 21220496






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 These data suggest that benzimidazole IGF-1R/InsR inhibitors may select for upregulation and be effluxed by the ATP-binding cassette transporter, BCRP, contributing to resistance. benzimidazole insulin like growth factor 1 receptor Homo sapiens