Title : BZW1 Facilitates Glycolysis and Promotes Tumor Growth in Pancreatic Ductal Adenocarcinoma Through Potentiating eIF2α Phosphorylation.

Pub. Date : 2022 Apr

PMID : 34951995






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In organoid-based xenografts with high BZW1 levels, both the PERK/eIF2alpha phosphorylation inhibitor GSK2606414 and ISRIB significantly suppressed tumor growth and prolonged animal survival. 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine eukaryotic translation initiation factor 2 alpha kinase 3 Homo sapiens