Pub. Date : 2016 Dec 19
PMID : 27989141
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | It is hypothesized that lapatinib-induced liver injury is caused by HLA-mediated antigen presentation to CD4 positive T cells. | Lapatinib | major histocompatibility complex, class II, DR beta 1 | Homo sapiens |
| 2 | However, analysis of PBMC and cloned T-cells from patients with HLA-DRB1*07:01-restricted lapatinib-induced liver injury revealed no evidence for drug-specific activation. | Lapatinib | major histocompatibility complex, class II, DR beta 1 | Homo sapiens |