| 1 |
34046359 | Recurrent Somatic MAP2K1 Mutations in Papillary Thyroid Cancer and Colorectal Cancer. | 2021 |
2 |
| 2 |
34247190 | The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis. | 2021 Aug |
3 |
| 3 |
31242404 | Integrin beta 4 (ITGB4) and its tyrosine-1510 phosphorylation promote pancreatic tumorigenesis and regulate the MEK1-ERK1/2 signaling pathway. | 2020 Feb 5 |
1 |
| 4 |
31830556 | Proliferative signaling by ERBB proteins and RAF/MEK/ERK effectors in polycystic kidney disease. | 2020 Mar |
1 |
| 5 |
26950759 | Phosphorylation or Mutation of the ERK2 Activation Loop Alters Oligonucleotide Binding. | 2016 Mar 29 |
1 |
| 6 |
27793200 | Subcellular localisation of pMEK has a different prognosis in locally advanced head and neck cancer treated with concomitant radiochemotherapy. | 2016 Oct 28 |
2 |
| 7 |
23820731 | A new model to evaluate Raf signaling in hematopoietic cells. | 2013 Sep |
1 |
| 8 |
21454680 | Mitogen-activated protein kinase kinase 1 (MEK1) stabilizes MyoD through direct phosphorylation at tyrosine 156 during myogenic differentiation. | 2011 May 27 |
2 |
| 9 |
18762250 | ERK-dependent threonine phosphorylation of EGF receptor modulates receptor downregulation and signaling. | 2008 Nov |
1 |
| 10 |
17293484 | In the yeast heat shock response, Hsf1-directed induction of Hsp90 facilitates the activation of the Slt2 (Mpk1) mitogen-activated protein kinase required for cell integrity. | 2007 Apr |
1 |
| 11 |
16931773 | Cooperation of matrix metalloproteinases with the RhoA/Rho kinase and mitogen-activated protein kinase kinase-1/extracellular signal-regulated kinase signaling pathways is required for the sphingosine-1-phosphate-induced mobilization of marrow-derived stromal cells. | 2006 Nov |
2 |
| 12 |
16148006 | ERK2 shows a restrictive and locally selective mechanism of recognition by its tyrosine phosphatase inactivators not shared by its activator MEK1. | 2005 Nov 11 |
1 |
| 13 |
14699120 | Tyrosine kinase, p56lck-induced cell motility, and urokinase-type plasminogen activator secretion involve activation of epidermal growth factor receptor/extracellular signal regulated kinase pathways. | 2004 Mar 12 |
1 |
| 14 |
15020233 | Glycogen synthase kinase-3beta is tyrosine-phosphorylated by MEK1 in human skin fibroblasts. | 2004 Apr 2 |
7 |
| 15 |
15031205 | Treatment with arsenic trioxide (ATO) and MEK1 inhibitor activates the p73-p53AIP1 apoptotic pathway in leukemia cells. | 2004 Jul 15 |
1 |
| 16 |
12554784 | Three mitogen-activated protein kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes. | 2003 Mar |
1 |
| 17 |
14674888 | Arsenite and arsenate activate extracellular signal-regulated kinases 1/2 by an epidermal growth factor receptor-mediated pathway in normal human keratinocytes. | 2003 Dec |
1 |
| 18 |
12082107 | The specificity of extracellular signal-regulated kinase 2 dephosphorylation by protein phosphatases. | 2002 Aug 30 |
2 |
| 19 |
8798409 | Angiotensin II interferes with interleukin 6-induced Stat3 signaling by a pathway involving mitogen-activated protein kinase kinase 1. | 1996 Sep 13 |
1 |
| 20 |
8034695 | Chemotactic peptides induce phosphorylation and activation of MEK-1 in human neutrophils. | 1994 Jul 29 |
2 |
| 21 |
8393135 | Identification and characterization of a new mammalian mitogen-activated protein kinase kinase, MKK2. | 1993 Aug |
2 |