Cholesterol

sterol regulatory element binding factor 2 ; Mus musculus







158 Article(s)
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1 35120997 LCN2 Mediates Skin Inflammation in Psoriasis through the SREBP2‒NLRC4 Axis. 2022 Feb 2 1
2 35184357 Targeted inhibition of PPARα ameliorates CLA-induced hypercholesterolemia via hepatic cholesterol biosynthesis reprogramming. 2022 Jun 2
3 35459869 AGR2-induced cholesterol synthesis drives lovastatin resistance that is overcome by combination therapy with allicin. 2022 Apr 22 2
4 35462473 Ch25h and 25-HC prevent liver steatosis through regulation of cholesterol metabolism and inflammation. 2022 Mar 25 2
5 33473285 Curcumin inhibits the proteolytic process of SREBP-2 by first inhibiting the expression of S1P rather than directly inhibiting SREBP-2 expression. 2021 Jan 1
6 33538705 Effects of ChREBP deficiency on adrenal lipogenesis and steroidogenesis. 2021 Mar 1
7 33685483 Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer's disease. 2021 Mar 8 2
8 33942715 Qki regulates myelinogenesis through Srebp2-dependent cholesterol biosynthesis. 2021 May 4 3
9 33945386 Upregulation of brain cholesterol levels inhibits mitophagy in Alzheimer disease. 2021 Jun 4
10 33974044 SREBP2 gene therapy targeting striatal astrocytes ameliorates Huntington's disease phenotypes. 2021 Nov 29 2
11 34021134 Qki activates Srebp2-mediated cholesterol biosynthesis for maintenance of eye lens transparency. 2021 May 21 5
12 34084908 Regulation of microRNA-33, SREBP and ABCA1 genes in a mouse model of high cholesterol. 2021 2
13 34158867 Lactate dehydrogenase B regulates macrophage metabolism in the tumor microenvironment. 2021 1
14 34281217 Muricholic Acids Promote Resistance to Hypercholesterolemia in Cholesterol-Fed Mice. 2021 Jul 2 1
15 34355142 ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function. 2021 Jul 23 2
16 34459531 p53 transcriptionally regulates SQLE to repress cholesterol synthesis and tumor growth. 2021 Oct 5 1
17 34507952 Metabolic Control of Sensory Neuron Survival by the p75 Neurotrophin Receptor in Schwann Cells. 2021 Oct 20 1
18 34554110 Contribution of high-fat diet-induced PCSK9 upregulation to a mouse model of PCOS is mediated partly by SREBP2. 2021 Oct 28 1
19 34600072 SIRT-1 Activity Sustains Cholesterol Synthesis in the Brain. 2021 Nov 10 1
20 34615375 Turnover Rates of the Low-Density Lipoprotein Receptor and PCSK9: Added Dimension to the Cholesterol Homeostasis Model. 2021 Dec 2
21 34644558 The cholesterol metabolite 25-hydroxycholesterol restrains the transcriptional regulator SREBP2 and limits intestinal IgA plasma cell differentiation. 2021 Oct 12 2
22 34836195 Fasting-Induced Upregulation of MKP-1 Modulates the Hepatic Response to Feeding. 2021 Nov 4 1
23 34859075 Loss of Hepatic Surf4 Depletes Lipid Droplets in the Adrenal Cortex but Does Not Impair Adrenal Hormone Production. 2021 4
24 30954949 Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans. 2020 Jan 1
25 31705742 SREBP2-STARD4 is involved in synthesis of cholesteryl ester stimulated by mono-butyl phthalate in MLTC-1 cells. 2020 Mar 1
26 32466086 Impact of the Gut Microbiota on Atorvastatin Mediated Effects on Blood Lipids. 2020 May 25 1
27 32500071 Brahma Related Gene 1 (Brg1) Regulates Cellular Cholesterol Synthesis by Acting as a Co-factor for SREBP2. 2020 4
28 32685494 Hydroxytyrosol Plays Antiatherosclerotic Effects through Regulating Lipid Metabolism via Inhibiting the p38 Signal Pathway. 2020 1
29 32766475 Lack of Augmenter of Liver Regeneration Disrupts Cholesterol Homeostasis of Liver in Mice by Inhibiting the AMPK Pathway. 2020 Aug 2
30 32926477 Rspo1/Rspo3-LGR4 signaling inhibits hepatic cholesterol synthesis through the AMPKα-SREBP2 pathway. 2020 Nov 2
31 32976883 NPY stimulates cholesterol synthesis acutely by activating the SREBP2-HMGCR pathway through the Y1 and Y5 receptors in murine hepatocytes. 2020 Dec 1 1
32 32985581 Wnt signaling mediates oncogenic synergy between Akt and Dlx5 in T-cell lymphomagenesis by enhancing cholesterol synthesis. 2020 Sep 28 2
33 33050202 The Crucial Role of Xanthine Oxidase in CKD Progression Associated with Hypercholesterolemia. 2020 Oct 9 1
34 33051352 Neutral Lipid Cacostasis Contributes to Disease Pathogenesis in Amyotrophic Lateral Sclerosis. 2020 Nov 18 2
35 33066385 Srebf2 Locus Overexpression Reduces Body Weight, Total Cholesterol and Glucose Levels in Mice Fed with Two Different Diets. 2020 Oct 14 2
36 33195535 Novel Lactobacillus reuteri HI120 Affects Lipid Metabolism in C57BL/6 Obese Mice. 2020 1
37 30384071 Pubertal exposure to the endocrine disruptor mono-2-ethylhexyl ester at body burden level caused cholesterol imbalance in mice. 2019 Jan 2
38 30515907 The sterol regulatory element-binding protein 2 is dysregulated by tau alterations in Alzheimer disease. 2019 Jul 3
39 30521806 Small Heterodimer Partner and Fibroblast Growth Factor 19 Inhibit Expression of NPC1L1 in Mouse Intestine and Cholesterol Absorption. 2019 Mar 3
40 30580964 p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression. 2019 Jan 24 1
41 30592221 Hypocholesterolemic Effect of the Lignin-Rich Insoluble Residue of Brewer's Spent Grain in Mice Fed a High-Fat Diet. 2019 Jan 30 1
42 30609251 Reactive oxygen species-induced changes in glucose and lipid metabolism contribute to the accumulation of cholesterol in the liver during aging. 2019 Apr 1
43 30679938 Dietary supplement of Smilax china L. ethanol extract alleviates the lipid accumulation by activating AMPK pathways in high-fat diet fed mice. 2019 1
44 30767299 Lipid markers and related transcripts during excitotoxic neurodegeneration in kainate-treated mice. 2019 Jul 2
45 30821074 A functional interaction between Hippo-YAP signalling and SREBPs mediates hepatic steatosis in diabetic mice. 2019 May 1
46 31013940 Mining for Oxysterols in Cyp7b1-/- Mouse Brain and Plasma: Relevance to Spastic Paraplegia Type 5. 2019 Apr 13 2
47 31299271 IFN-α-2b treatment protects against diet-induced obesity and alleviates non-alcoholic fatty liver disease in mice. 2019 Sep 15 1
48 31327168 Industrial Trans Fatty Acids Stimulate SREBP2-Mediated Cholesterogenesis and Promote Non-Alcoholic Fatty Liver Disease. 2019 Oct 1
49 31376793 Oxidative inactivation of amyloid beta-degrading proteases by cholesterol-enhanced mitochondrial stress. 2019 Sep 1
50 31387993 Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export. 2019 Aug 6 1