Cholesterol

sterol regulatory element binding factor 2 ; Mus musculus







158 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
51 31470036 Bisphenol A exposure induces cholesterol synthesis and hepatic steatosis in C57BL/6 mice by down-regulating the DNA methylation levels of SREBP-2. 2019 Nov 1
52 31547031 Allium hookeri Root Extract Inhibits Adipogenesis by Promoting Lipolysis in High Fat Diet-Induced Obese Mice. 2019 Sep 20 1
53 31849474 Heterozygous Disruption of Beclin 1 Alleviates Zinc Oxide Nanoparticles-Induced Disturbance of Cholesterol Biosynthesis in Mouse Liver. 2019 2
54 28828594 Does Sirt2 Regulate Cholesterol Biosynthesis During Oligodendroglial Differentiation In Vitro and In Vivo? 2018 Jan 1
55 29137983 Transcriptional regulation of acetoacetyl-CoA synthetase by Sp1 in neuroblastoma cells. 2018 Jan 1 1
56 29172112 Cholesterol-lowering effects of dietary pomegranate extract and inulin in mice fed an obesogenic diet. 2018 Feb 1
57 29243365 Vitamin A-coupled liposome system targeting free cholesterol accumulation in hepatic stellate cells offers a beneficial therapeutic strategy for liver fibrosis. 2018 Apr 2
58 29274780 Follicle-stimulating hormone promotes the transformation of cholesterol to estrogen in mouse adipose tissue. 2018 Jan 15 1
59 29286073 Proteasome inhibition protects against diet-induced gallstone formation through modulation of cholesterol and bile acid homeostasis. 2018 Mar 1
60 29499335 Metformin treatment prevents SREBP2-mediated cholesterol uptake and improves lipid homeostasis during oxidative stress-induced atherosclerosis. 2018 Apr 8
61 29678744 Long noncoding RNA lncARSR promotes hepatic cholesterol biosynthesis via modulating Akt/SREBP-2/HMGCR pathway. 2018 Jun 15 2
62 29853881 Beta-Arrestin 1 Mediates Liver Thyrotropin Regulation of Cholesterol Conversion Metabolism via the Akt-Dependent Pathway. 2018 1
63 29862881 Cholesterol impairs autophagy-mediated clearance of amyloid beta while promoting its secretion. 2018 1
64 28011404 Regulation of SREBP-2 intracellular trafficking improves impaired autophagic flux and alleviates endoplasmic reticulum stress in NAFLD. 2017 Mar 3
65 28096339 Loss of astrocyte cholesterol synthesis disrupts neuronal function and alters whole-body metabolism. 2017 Jan 31 1
66 28126350 Peptostreptococcus anaerobius Induces Intracellular Cholesterol Biosynthesis in Colon Cells to Induce Proliferation and Causes Dysplasia in Mice. 2017 May 1
67 28213272 Rev-erb regulation of cholesterologenesis. 2017 May 1 1
68 28244871 Expression of SREBP-1c Requires SREBP-2-mediated Generation of a Sterol Ligand for LXR in Livers of Mice. 2017 Feb 28 2
69 28395113 A novel role for CRTC2 in hepatic cholesterol synthesis through SREBP-2. 2017 Aug 8
70 28501578 Anhydroicaritin, a SREBPs inhibitor, inhibits RANKL-induced osteoclastic differentiation and improves diabetic osteoporosis in STZ-induced mice. 2017 Aug 15 1
71 28628040 Lipogenic transcription factor ChREBP mediates fructose-induced metabolic adaptations to prevent hepatotoxicity. 2017 Jun 30 2
72 28630260 Cholesterol auxotrophy and intolerance to ezetimibe in mice with SREBP-2 deficiency in the intestine. 2017 Oct 3
73 28676202 Hexacosanol reduces plasma and hepatic cholesterol by activation of AMP-activated protein kinase and suppression of sterol regulatory element-binding protein-2 in HepG2 and C57BL/6J mice. 2017 Jul 2
74 28774869 Overactivation of intestinal sterol response element-binding protein 2 promotes diet-induced nonalcoholic steatohepatitis. 2017 Nov 1 3
75 28794002 Krüppel-Like Factor 4 Regulation of Cholesterol-25-Hydroxylase and Liver X Receptor Mitigates Atherosclerosis Susceptibility. 2017 Oct 3 2
76 26685326 SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression. 2016 Mar 2
77 26872317 The moderate essential amino acid restriction entailed by low-protein vegan diets may promote vascular health by stimulating FGF21 secretion. 2016 Feb 12 3
78 27013235 The LATS2 tumor suppressor inhibits SREBP and suppresses hepatic cholesterol accumulation. 2016 Apr 1 1
79 27211556 Irisin Inhibits Hepatic Cholesterol Synthesis via AMPK-SREBP2 Signaling. 2016 Apr 1
80 27435541 Functional Probiotic Characterization and In Vivo Cholesterol-Lowering Activity of Lactobacillus helveticus Isolated from Fermented Cow Milk. 2016 Oct 28 1
81 27679530 Perilipin-2 Deletion Impairs Hepatic Lipid Accumulation by Interfering with Sterol Regulatory Element-binding Protein (SREBP) Activation and Altering the Hepatic Lipidome. 2016 Nov 11 1
82 25646300 Matrix metalloproteinase-2 mediates a mechanism of metabolic cardioprotection consisting of negative regulation of the sterol regulatory element-binding protein-2/3-hydroxy-3-methylglutaryl-CoA reductase pathway in the heart. 2015 Apr 1
83 25693659 Ergostatrien-3β-ol from Antrodia camphorata inhibits diabetes and hyperlipidemia in high-fat-diet treated mice via regulation of hepatic related genes, glucose transporter 4, and AMP-activated protein kinase phosphorylation. 2015 Mar 11 1
84 25757506 Opposing roles of nitric oxide and rho-kinase in lipid metabolism in mice. 2015 Mar 1
85 25777360 ITCH modulates SIRT6 and SREBP2 to influence lipid metabolism and atherosclerosis in ApoE null mice. 2015 Mar 17 1
86 25794851 Fibroblast growth factor 21 prevents atherosclerosis by suppression of hepatic sterol regulatory element-binding protein-2 and induction of adiponectin in mice. 2015 May 26 1
87 25916803 Ezetimibe and simvastatin modulate gut microbiota and expression of genes related to cholesterol metabolism. 2015 Jul 1 2
88 26184741 Fibronectin Overexpression Modulates Formation of Macrophage Foam Cells by Activating SREBP2 Involved in Endoplasmic Reticulum Stress. 2015 2
89 26370080 Effect of cholesterol reduction on receptor signaling in neurons. 2015 Oct 30 2
90 26528138 Lysosomal and phagocytic activity is increased in astrocytes during disease progression in the SOD1 (G93A) mouse model of amyotrophic lateral sclerosis. 2015 2
91 26634251 Liver ChIP-seq analysis in FGF19-treated mice reveals SHP as a global transcriptional partner of SREBP-2. 2015 Dec 4 2
92 23832448 Free cholesterol accumulation in hepatic stellate cells: mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice. 2014 Jan 1
93 24211592 Cholesterol biosynthesis and ER stress in peroxisome deficiency. 2014 Mar 4
94 24337570 Insig proteins mediate feedback inhibition of cholesterol synthesis in the intestine. 2014 Jan 24 3
95 24465397 Overactivation of intestinal SREBP2 in mice increases serum cholesterol. 2014 8
96 23203768 Prebiotic approach alleviates hepatic steatosis: implication of fatty acid oxidative and cholesterol synthesis pathways. 2013 Feb 1
97 23347841 25-Hydroxycholesterol regulates cholesterol homeostasis in the murine CATH.a neuronal cell line. 2013 Feb 28 1
98 23536474 Regulation of cholesterol and bile acid homeostasis by the cholesterol 7α-hydroxylase/steroid response element-binding protein 2/microRNA-33a axis in mice. 2013 Sep 4
99 23585733 Reduction of the cholesterol sensor SCAP in the brains of mice causes impaired synaptic transmission and altered cognitive function. 2013 2
100 23648430 APP/PS1 mice overexpressing SREBP-2 exhibit combined Aβ accumulation and tau pathology underlying Alzheimer's disease. 2013 Sep 1 1