Title : IFN-α-2b treatment protects against diet-induced obesity and alleviates non-alcoholic fatty liver disease in mice.

Pub. Date : 2019 Sep 15

PMID : 31299271






1 Functional Relationships(s)
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1 Mechanistically, we found that IFN-alpha-2b antiobesity effects were related to increased fatty acid oxidation; and its effects on cholesterol metabolism were due to both a decrease in the master cholesterogenic transcription factor SREBP-2 and in the rate limiting enzyme in cholesterol synthesis, HMGCR. Cholesterol sterol regulatory element binding factor 2 Mus musculus