| 1 |
31060578 | Late-onset thymidine kinase 2 deficiency: a review of 18 cases. | 2019 May 6 |
1 |
| 2 |
29602790 | Retrospective natural history of thymidine kinase 2 deficiency. | 2018 Aug |
2 |
| 3 |
31459030 | Negative Cooperative Binding of Thymidine, Ordered Substrate Binding, and Product Release of Human Mitochondrial Thymidine Kinase 2 Explain Its Complex Kinetic Properties and Physiological Functions. | 2018 Aug 31 |
5 |
| 4 |
25215937 | Thymidine kinase 2 enzyme kinetics elucidate the mechanism of thymidine-induced mitochondrial DNA depletion. | 2014 Oct 7 |
6 |
| 5 |
22571666 | Recent advances in thymidine kinase 2 (TK2) inhibitors and new perspectives for potential applications. | 2012 |
2 |
| 6 |
21444706 | The kinetic effects on thymidine kinase 2 by enzyme-bound dTTP may explain the mitochondrial side effects of antiviral thymidine analogs. | 2011 Jun |
5 |
| 7 |
21491329 | A mathematical model of human thymidine kinase 2 activity. | 2011 Mar |
5 |
| 8 |
20083405 | Two novel mutations in thymidine kinase-2 cause early onset fatal encephalomyopathy and severe mtDNA depletion. | 2010 Mar |
1 |
| 9 |
20218622 | 3'-[4-Aryl-(1,2,3-triazol-1-yl)]-3'-deoxythymidine analogues as potent and selective inhibitors of human mitochondrial thymidine kinase. | 2010 Apr 8 |
1 |
| 10 |
20544521 | Enzymatic regulation of cytosolic thymidine kinase 1 and mitochondrial thymidine kinase 2: a mini review. | 2010 Jun |
1 |
| 11 |
19154348 | Unchanged thymidine triphosphate pools and thymidine metabolism in two lines of thymidine kinase 2-mutated fibroblasts. | 2009 Feb |
2 |
| 12 |
19233899 | Human mitochondrial thymidine kinase is selectively inhibited by 3'-thiourea derivatives of beta-thymidine: identification of residues crucial for both inhibition and catalytic activity. | 2009 May |
2 |
| 13 |
20560637 | Nonpolar nucleoside mimics as active substrates for human thymidine kinases. | 2009 Apr 22 |
1 |
| 14 |
18455811 | Substrate specificity of feline and canine herpesvirus thymidine kinase. | 2008 Aug |
1 |
| 15 |
18600552 | 5-Bromovinyl 2'-deoxyuridine phosphorylation by mitochondrial and cytosolic thymidine kinase (TK2 and TK1) and its use in selective measurement of TK2 activity in crude extracts. | 2008 Jun |
1 |
| 16 |
17266931 | Mutagenesis of non-conserved active site residues improves the activity and narrows the specificity of human thymidine kinase 2. | 2007 Mar 16 |
1 |
| 17 |
17913703 | Mitochondrial thymidine kinase and the enzymatic network regulating thymidine triphosphate pools in cultured human cells. | 2007 Nov 30 |
5 |
| 18 |
16630572 | Bromovinyl-deoxyuridine: A selective substrate for mitochondrial thymidine kinase in cell extracts. | 2006 May 26 |
1 |
| 19 |
17181158 | N1-substituted thymine derivatives as mitochondrial thymidine kinase (TK-2) inhibitors. | 2006 Dec 28 |
1 |
| 20 |
15628745 | Phosphorylation of isocarbostyril- and difluorophenyl-nucleoside thymidine mimics by the human deoxynucleoside kinases. | 2004 |
1 |
| 21 |
14690426 | Tight binding of deoxyribonucleotide triphosphates to human thymidine kinase 2 expressed in Escherichia coli. Purification and partial characterization of its dimeric and tetrameric forms. | 2003 Dec 30 |
1 |
| 22 |
12123744 | 3'-Azido-2',3'-dideoxythymidine induced deficiency of thymidine kinases 1, 2 and deoxycytidine kinase in H9 T-lymphoid cells. | 2002 Jul 15 |
1 |
| 23 |
11266658 | 2'-O-Acyl/alkyl-substituted arabinosyl nucleosides as inhibitors of human mitochondrial thymidine kinase. | 2001 Mar 15 |
1 |
| 24 |
11687801 | Mutant mitochondrial thymidine kinase in mitochondrial DNA depletion myopathy. | 2001 Nov |
1 |
| 25 |
10799656 | Expression of human mitochondrial thymidine kinase in Escherichia coli: correlation between the enzymatic activity of pyrimidine nucleoside analogues and their inhibitory effect on bacterial growth. | 2000 Jun 15 |
1 |
| 26 |
9461577 | Four deoxynucleoside kinase activities from Drosophila melanogaster are contained within a single monomeric enzyme, a new multifunctional deoxynucleoside kinase. | 1998 Feb 13 |
1 |
| 27 |
9079672 | Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2. | 1997 Mar 28 |
1 |
| 28 |
9359870 | Relaxed enantioselectivity of human mitochondrial thymidine kinase and chemotherapeutic uses of L-nucleoside analogues. | 1997 Nov 15 |
2 |
| 29 |
8726039 | Phosphorylation of the anti-hepatitis B nucleoside analog 1-(2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl)-5-iodouracil (FIAU) by human cytosolic and mitochondrial thymidine kinase and implications for cytotoxicity. | 1996 Jun |
1 |
| 30 |
7572355 | Human thymidine kinase 1. Regulation in normal and malignant cells. | 1995 |
1 |
| 31 |
7637389 | Increased ratio between deoxycytidine kinase and thymidine kinase 2 in CLL lymphocytes compared to normal lymphocytes. | 1995 Jul |
1 |
| 32 |
1597439 | Thymidine and 3'-azido-3'-deoxythymidine metabolism in human peripheral blood lymphocytes and monocyte-derived macrophages. A study of both anabolic and catabolic pathways. | 1992 Jun 5 |
1 |
| 33 |
2026611 | Diverging substrate specificity of pure human thymidine kinases 1 and 2 against antiviral dideoxynucleosides. | 1991 May 15 |
2 |
| 34 |
6504022 | Differences in the kinetic properties of thymidine kinase isoenzymes in unstimulated and phytohemagglutinin-stimulated human lymphocytes. | 1984 Sep |
2 |