Title : Mitochondrial thymidine kinase and the enzymatic network regulating thymidine triphosphate pools in cultured human cells.

Pub. Date : 2007 Nov 30

PMID : 17913703






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 In non-proliferating cells mitochondrial (mt) thymidine kinase (TK2) salvages thymidine derived from the extracellular milieu for the synthesis of mt dTTP. Thymidine thymidine kinase 2 Homo sapiens
2 The activity of TK2 is curbed by thymidine phosphorylase, which degrades thymidine in the cytoplasm, thus limiting the availability of thymidine for phosphorylation by TK2 in mitochondria. Thymidine thymidine kinase 2 Homo sapiens
3 The activity of TK2 is curbed by thymidine phosphorylase, which degrades thymidine in the cytoplasm, thus limiting the availability of thymidine for phosphorylation by TK2 in mitochondria. Thymidine thymidine kinase 2 Homo sapiens
4 The activity of TK2 is curbed by thymidine phosphorylase, which degrades thymidine in the cytoplasm, thus limiting the availability of thymidine for phosphorylation by TK2 in mitochondria. Thymidine thymidine kinase 2 Homo sapiens
5 The activity of TK2 is curbed by thymidine phosphorylase, which degrades thymidine in the cytoplasm, thus limiting the availability of thymidine for phosphorylation by TK2 in mitochondria. Thymidine thymidine kinase 2 Homo sapiens