Title : Nonpolar nucleoside mimics as active substrates for human thymidine kinases.

Pub. Date : 2009 Apr 22

PMID : 20560637






1 Functional Relationships(s)
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1 We describe the use of nonpolar nucleoside analogues of systematically varied size and shape to probe the mechanisms by which the two human thymidine kinases (TK1 and TK2) recognize and phosphorylate their substrate, thymidine. Thymidine thymidine kinase 2 Homo sapiens